“… 48 With formal approval by the U.S. Food and Drug Administration (FDA) Zyderm Collagen™ became the preferred tissue filler in the 1980s. 49 S. Stegman, T. Tromovitch, M. Elson, F. Brandt, A. Klein, and W. Hanke lead the effort to develop proper surgical techniques for use of bovine collagen materials. Recently, injectable human collagen has become available, and it remains to be seen whether this will decrease the use of bovine collagen in dermatology.…”