Initial management strategies for dyspepsia

Critical appraisal of international guidelines for the management of Helicobacter pylori infection in case of dyspepsia

“…Recent studies confirm that the benefit brought by the eradication treatment is observed 6 to 12 months after its end, which would correspond to the time of cure of the gastritis 46 . Moreover, the number of patients to be treated to obtain recovery is between 8 and 14 according to the studies 47,48 . As regard to the improvement of the quality of life of the patients, no difference was shown between HP eradication treatment and PPI treatment or placebo 26 .…”

“…46 Moreover, the number of patients to be treated to obtain recovery is between 8 and 14 according to the studies. 47,48 As regard to the improvement of the quality of life of the patients, no difference was shown between HP eradication treatment and PPI treatment or placebo. 26 As a result, due to slightly effective or ineffective treatment and side effects that may not be well accepted by patients (headaches, digestive or allergic disorders), other alternatives have been developed (prokinetics, tricyclic antidepressants, CBT).…”

Critical appraisal of international guidelines for the management of Helicobacter pylori infection in case of dyspepsia

“…Recent studies confirm that the benefit brought by the eradication treatment is observed 6 to 12 months after its end, which would correspond to the time of cure of the gastritis 46 . Moreover, the number of patients to be treated to obtain recovery is between 8 and 14 according to the studies 47,48 . As regard to the improvement of the quality of life of the patients, no difference was shown between HP eradication treatment and PPI treatment or placebo 26 .…”

“…46 Moreover, the number of patients to be treated to obtain recovery is between 8 and 14 according to the studies. 47,48 As regard to the improvement of the quality of life of the patients, no difference was shown between HP eradication treatment and PPI treatment or placebo. 26 As a result, due to slightly effective or ineffective treatment and side effects that may not be well accepted by patients (headaches, digestive or allergic disorders), other alternatives have been developed (prokinetics, tricyclic antidepressants, CBT).…”

Effect of Amitriptyline and Escitalopram on Functional Dyspepsia: A Multicenter, Randomized Controlled Study

“…As a prior study has shown that the yield from EGD in functional dyspepsia is low in the absence of alarm features 38 and a meta-analysis in FD found that endoscopy was not superior to empiric acid suppression in terms of outcomes, the likelihood of misclassification of FD appears low. 39 …”

The Comparative Study of the Effectiveness of Cimetidine, Ranitidine, Famotidine, and Omeprazole in Treatment of Children With Dyspepsia

“…In another study, it was found that Famotidine was equally effective as placebo [6] . In a meta-analysis, proton pump inhibitors were regarded as superior to H2-receptor antagonists and antacids in patients with -non investigated‖ dyspepsia [13] , H2-receptor antagonists and antacids showed positive effects in approximately 40% of patients (which is in the range of the placebo response rate) whereas proton pump inhibitors response rates were significantly higher, adding an additional 20% [1] . In two preliminary studies of…”

Critical appraisal of international guidelines for the management of Helicobacter pylori infection in case of dyspepsia

“…Recent studies confirm that the benefit brought by the eradication treatment is observed 6 to 12 months after its end, which would correspond to the time of cure of the gastritis 46 . Moreover, the number of patients to be treated to obtain recovery is between 8 and 14 according to the studies 47,48 . As regard to the improvement of the quality of life of the patients, no difference was shown between HP eradication treatment and PPI treatment or placebo 26 .…”

“…46 Moreover, the number of patients to be treated to obtain recovery is between 8 and 14 according to the studies. 47,48 As regard to the improvement of the quality of life of the patients, no difference was shown between HP eradication treatment and PPI treatment or placebo. 26 As a result, due to slightly effective or ineffective treatment and side effects that may not be well accepted by patients (headaches, digestive or allergic disorders), other alternatives have been developed (prokinetics, tricyclic antidepressants, CBT).…”

Effect of Amitriptyline and Escitalopram on Functional Dyspepsia: A Multicenter, Randomized Controlled Study

“…As a prior study has shown that the yield from EGD in functional dyspepsia is low in the absence of alarm features 38 and a meta-analysis in FD found that endoscopy was not superior to empiric acid suppression in terms of outcomes, the likelihood of misclassification of FD appears low. 39 …”

The Comparative Study of the Effectiveness of Cimetidine, Ranitidine, Famotidine, and Omeprazole in Treatment of Children With Dyspepsia

“…In another study, it was found that Famotidine was equally effective as placebo [6] . In a meta-analysis, proton pump inhibitors were regarded as superior to H2-receptor antagonists and antacids in patients with -non investigated‖ dyspepsia [13] , H2-receptor antagonists and antacids showed positive effects in approximately 40% of patients (which is in the range of the placebo response rate) whereas proton pump inhibitors response rates were significantly higher, adding an additional 20% [1] . In two preliminary studies of…”

Critical appraisal of international guidelines for the management of Helicobacter pylori infection in case of dyspepsia

“…Recent studies confirm that the benefit brought by the eradication treatment is observed 6 to 12 months after its end, which would correspond to the time of cure of the gastritis 46 . Moreover, the number of patients to be treated to obtain recovery is between 8 and 14 according to the studies 47,48 . As regard to the improvement of the quality of life of the patients, no difference was shown between HP eradication treatment and PPI treatment or placebo 26 .…”

“…46 Moreover, the number of patients to be treated to obtain recovery is between 8 and 14 according to the studies. 47,48 As regard to the improvement of the quality of life of the patients, no difference was shown between HP eradication treatment and PPI treatment or placebo. 26 As a result, due to slightly effective or ineffective treatment and side effects that may not be well accepted by patients (headaches, digestive or allergic disorders), other alternatives have been developed (prokinetics, tricyclic antidepressants, CBT).…”

Effect of Amitriptyline and Escitalopram on Functional Dyspepsia: A Multicenter, Randomized Controlled Study

“…As a prior study has shown that the yield from EGD in functional dyspepsia is low in the absence of alarm features 38 and a meta-analysis in FD found that endoscopy was not superior to empiric acid suppression in terms of outcomes, the likelihood of misclassification of FD appears low. 39 …”

The Comparative Study of the Effectiveness of Cimetidine, Ranitidine, Famotidine, and Omeprazole in Treatment of Children With Dyspepsia

“…In another study, it was found that Famotidine was equally effective as placebo [6] . In a meta-analysis, proton pump inhibitors were regarded as superior to H2-receptor antagonists and antacids in patients with -non investigated‖ dyspepsia [13] , H2-receptor antagonists and antacids showed positive effects in approximately 40% of patients (which is in the range of the placebo response rate) whereas proton pump inhibitors response rates were significantly higher, adding an additional 20% [1] . In two preliminary studies of…”