Initial Experience and Evaluation of a Nomogram for Outcome Prediction in Management of Medium-sized (1–2 cm) Kidney Stones

Micali, Salvatore; Sighinolfi, Maria Chiara; Iseppi, A.; Morini, Elena; Calcagnile, Tommaso; Benedetti, Mattia; Ticonosco, M.; Kaleci, Shaniko; Bevilacqua, L.; Puliatti, Stefano; Nunzio, Cosimo De; Arada, Raphael; Chiancone, Francesco; Campobasso, Davide; Eissa, Ahmed; Bonfante, Giulia; Simonetti, Elisa; Cotugno, Michele; Galli, R.; Curti, P.; Schips, Luigi; Ditonno, Pasquale; Villa, Luca; Ferretti, Stefania; Bergamaschi, F.; Bozzini, Giorgio; Zoeir, Ahmed; Sherbiny, Ahmed El; Frattini, Antonio; Fedelini, Paolo; Okhunov, Zhamshid; Tubaro, Andrea; Landman, Jaime; Bianchi, G; Rocco, Bernardo

doi:10.1016/j.euf.2020.12.012

Cited by 11 publications

(7 citation statements)

References 29 publications

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“…To selection criteria of scoring systems, Resorlu-Unsal Score (RUS), modified Seoul National University Renal Stone Complexity Score (S-ReSC), R.I.R.S., S.T.O.N.E., and Ito’s nomogram were selected and relevant studies included in the systematic review. (T)allness, (O)ccupied lesion and (HO)unsfield units (T.O.HO) score and 2 nomograms were excluded due to the lack of external validation [ 9 , 10 , 11 ]. Also one nomogram which developed for pediatric patients and one nomogram predicting perioperative complications were excluded [ 12 , 13 ].…”

Section: Resultsmentioning

confidence: 99%

Recent scoring systems predicting stone-free status after retrograde intrarenal surgery; a systematic review and meta-analysis

Özman

Akgül

Başataç

et al. 2022

Cent european J Urol

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Introduction Several scoring systems and nomograms have been developed to predict the success of retrograde intrarenal surgery. But no meta-analysis for the performance of scoring systems has yet been performed. The aim of this study was to compare predictive ability of recent scoring systems for stone-free rate of retrograde intrarenal surgery. Material and methods PubMed and Web of Science databases were searched systematically between April and May 2021. The scoring systems which were validated externally or studied at least by two different researcher groups were selected for further analysis. Of 59 records, 14 studies met the inclusion criteria (n = 4137). Area under curve (AUC) values of selected scoring systems were pooled in random or fixed effects. The I 2 test was used to quantify heterogeneity. Results Eight, 5, 8, 4 and 3 studies included in meta-analyses for the modified Seoul National University Renal Stone Complexity Score (S-ReSC), R.I.R.S., Resorlu-Unsal Score (RUS), S.T.O.N.E., and Ito’s Nomogram, respectively. We found pooled AUC values 0.709 (95% CI 0.670–0.748), 0.704 (95% CI 0.668–0.739), 0.669 (95% CI 0.646 to 0.692), and 0.771 (95% CI 0.724 to 0.818), for first four of them, respectively. Heterogeneity was very high to pool AUC values for Ito’s nomogram. Conclusions Although S.T.O.N.E. score showed higer pooled AUC value, this systematic review and meta-analysis has not revealed superiority of any scoring system. High heterogeneity between studies and dependencies between scoring systems make it difficult to design a comparative statistical model to generalize the findings. Also, limitations aside, neither scoring system has demonstrated good predictive/discriminative performance.

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Section: Resultsmentioning

confidence: 99%

Recent scoring systems predicting stone-free status after retrograde intrarenal surgery; a systematic review and meta-analysis

Özman

Akgül

Başataç

et al. 2022

Cent european J Urol

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“…This may imply that this size spectrum is the most confusing on the scale of stone size relative to the numerous available treatment options, such as SWL, PNL, RIRS, and their varieties and combinations. [1,3,14,17] This confusion revealed a continuous need to refine the decision-making process in the context of rapid changes and advances in the field of endourology. [3,9] The current series of patients with a stone size of 10 to 20 mm examined a specific point of refining the predictors of SWL success, which was the SFR after a single-session SWL, similar to other studies.…”

Section: Discussionmentioning

confidence: 99%

“…[2,12,13] However, the criterion standard option for medium stones has not been defined yet. [13,14] Thus, research trials are being conducted to study different modalities of treatment. This study aimed to refine the evidence for decision making in the context of the evolving demands of increasing populations, technological advancements, and the current coronavirus disease 2019 (COVID-19) pandemic.…”

Section: Introductionmentioning

confidence: 99%

“…This study aimed to refine the evidence for decision making in the context of the evolving demands of increasing populations, technological advancements, and the current coronavirus disease 2019 (COVID-19) pandemic. [2,3,9,11,14,15] Therefore, the ability to identify which stone cases will respond successfully to SWL remains a point of research that represents the backbone of our rationale for conducting this retrospective study.…”

Section: Introductionmentioning

confidence: 99%

“…[9][10][11][12][13][14][15][16][17][18][19][20][21][22][23][24][25] Transverse diameter of the stone, mean ± SD (range), mm 10.8 ± 3.9(3)(4)(5)(6)(7)(8)(9)(10)(11)(12)(13)(14)(15)(16)(17)(18)(19)(20)(21)(22) BMI = body mass index; HU = Hounsfield unit; SD = standard deviation; UPJ = ureteropelvic junction.…”

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Predictors of stone-free rate after a single-session extracorporeal shockwave lithotripsy for a single kidney stone measuring 10 to 20 mm: A private center experience

Faddan¹,

Najieb²,

Gadelkareem³

2022

Curr Urol

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Background: Despite the continuous update of guidelines for the management of kidney stones, the ability to predict a successful response to extracorporeal shockwave lithotripsy (SWL) remains a topic of research. This is due to the need to refine the decision making in the context of technological advancements and current pandemics. This study aimed to determine the predictors of stone-free rate (SFR) after single-session SWL in adult patients with a single kidney stone 10 to 20 mm in diameter. Materials and methods: A retrospective review of the records of patients with a single kidney stone 10 to 20 mm in diameter was performed at a private SWL center from December 2019 to February 2021. Univariate and multivariate analyses were performed for stoneand patient-related factors, using the Student t and Mann-Whitney U tests for the quantitative variables and the Fisher exact and Pearson correlation tests for the qualitative variables. Results: A total of 138 patients were eligible for this study, including 92 men and 46 women. The mean age was 38.6 ± 12.4years, and the mean body mass index (BMI) was 25.9 ± 3.4kg/m 2 . Four weeks after SWL, 120 patients (87%) were free of stones, and 18 (13%) needed further treatment. Univariate analyses showed that SFR was negatively correlated with increased BMI ( p = 0.0001), maximum stone length ( p = 0.0001), transverse diameter of the stone ( p = 0.0001), number of shocks per session ( p = 0.052), and Hounsfield unit (HU) ( p = 0.0001). Multivariate analysis revealed that HU ( p = 0.009), maximum stone length ( p = 0.01), BMI ( p = 0.000), and presence of double-J stent ( p = 0.034) were independent risk factors for failure of single-session SWL in the treatment of kidney stones 10 to 20 mm in diameter. The estimated average cost per case was USD 450.5. Conclusions: Increased HU, maximum stone length, BMI, and presence of double-J stents were independent risk factors for low SFR after single-session SWL for a kidney stone 10 to 20 mm in diameter. The cost of SWL remains an advantage in the private sector.

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Volume should be used instead of diameter for kidney stones between 10 and 20 mm to determine the type of surgery and increase success

et al. 2022

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Initial Experience and Evaluation of a Nomogram for Outcome Prediction in Management of Medium-sized (1–2 cm) Kidney Stones

Cited by 11 publications

References 29 publications

Recent scoring systems predicting stone-free status after retrograde intrarenal surgery; a systematic review and meta-analysis

Recent scoring systems predicting stone-free status after retrograde intrarenal surgery; a systematic review and meta-analysis

Predictors of stone-free rate after a single-session extracorporeal shockwave lithotripsy for a single kidney stone measuring 10 to 20 mm: A private center experience

Volume should be used instead of diameter for kidney stones between 10 and 20 mm to determine the type of surgery and increase success

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