Inhibitory effects of kaempferol, quercetin and luteolin on the replication of human parainfluenza virus type 2 <i>in vitro </i>
Kae Sakai-Sugino,
Jun Uematsu,
Hidetaka Yamamoto
et al.
Abstract:Virus replication, flavonoid, recombinant green fluorescence protein-expressing hPIV-2 without matrix proteinThe eight flavonoids, apigenin, chrysin, hesperidin, kaempferol, myricetin, quercetin, rutin and luteolin were tested for the inhibition of human parainfluenza virus type 2 (hPIV-2) replication. Three flavonoids out of the eight, kaempferol, quercetin and luteolin inhibited hPIV-2 replication. Kaempferol reduced the virus release (below 1/10,000), partly inhibited genome and mRNA syntheses, but protein … Show more
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