2016
DOI: 10.1371/journal.pone.0166477 View full text |Buy / Rent full text
|
|

Abstract: Cholera toxin (CT) is an AB-type protein toxin that contains a catalytic A1 subunit, an A2 linker, and a cell-binding B homopentamer. The CT holotoxin is released into the extracellular environment, but CTA1 attacks a target within the cytosol of a host cell. We recently reported that grape extract confers substantial resistance to CT. Here, we used a cell culture system to identify twelve individual phenolic compounds from grape extract that inhibit CT. Additional studies determined the mechanism of inhibitio… Show more

Help me understand this report

Search citation statements

Order By: Relevance
Select...
0
19
0

Publication Types

Select...

Relationship

0
0

Authors

Journals