2016
DOI: 10.18632/aging.100896
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Abstract: Alzheimer's disease is one of the most significant healthcare problems today, with a dire need for effective treatment. Identifying subtypes of Alzheimer's disease may aid in the development of therapeutics, and recently three different subtypes have been described: type 1 (inflammatory), type 2 (non-inflammatory or atrophic), and type 3 (cortical). Here I report that type 3 Alzheimer's disease is the result of exposure to specific toxins, and is most commonly inhalational (IAD), a phenotypic manifestation of … Show more

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Cited by 28 publications
(17 citation statements)
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References 12 publications
(17 reference statements)
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“…Social as well as economical costs of AD prevention and cure require improved methods of diagnosis and treatment. There are currently no effective treatment for AD [40], no biomarkers for early diagnosis of AD and the pathogenesis of AD is uncertain even now [22,41]. Therefore, it is vital to expand our knowledge of AD pathogenic mechanisms or we will nearly fail to develop efficient therapies for AD.…”
Section: Authors Contributionmentioning
confidence: 99%
“…Social as well as economical costs of AD prevention and cure require improved methods of diagnosis and treatment. There are currently no effective treatment for AD [40], no biomarkers for early diagnosis of AD and the pathogenesis of AD is uncertain even now [22,41]. Therefore, it is vital to expand our knowledge of AD pathogenic mechanisms or we will nearly fail to develop efficient therapies for AD.…”
Section: Authors Contributionmentioning
confidence: 99%
“…and prescribes an intervention as a 'disease modifying therapy' (DMT) that targets change in the underlying disease process leading to cell death [52]. The mechanisms and determinants are many [53] and predominantly involve nutritional deficiency [54], inflammation [55], oxidative stress [56], mitochondrial dysfunction [57], impaired methylation pathways [58], impaired Aβ clearance [43], hormone imbalance [59], chronic stress [60], gut dysbiosis [61], insulin dysregulation [62], infections [40,[63][64][65][66], poor sleep [67], vascular disease [68], and toxicity [41,60,69,70], including heavy metals [71][72][73][74][75].…”
Section: The Logic Of Applying Personalised Medicine To Cognitive Decmentioning
confidence: 99%
“…43 Other research suggests that Alzheimer's disease is caused by inhalation of biotoxins and mycotoxins from fungi which manifests as chronic inflammatory response syndrome. 44 Therefore, we shouldn't underestimate the role that fungi play in the aetiology of a diverse range of unwanted illness events.…”
Section: Other Risksmentioning
confidence: 99%