Influenza-Associated Hemophagocytic Syndrome in Adults: Case Report and Review

Trujillo, Hernando; Lalueza, Antonio; Blanco, Marta Corral; Folgueira, Dolores; González-Gómez, Carlos; Lumbreras, Carlos

doi:10.4172/1948-5964.1000172

Cited by 1 publication

(1 citation statement)

References 21 publications

Supporting

Mentioning

Contrasting

Order By: Relevance

“…In addition, some patients may require utilization of heparin, ECMO and/or CRRT treatment (162). Avian flu with cytokine storm might be associated with augmented immune responses such as hemophagocytosis showing anemia, thrombocytopenia, hyperferritinemia, hypertriglyceridemia, and adult type respiratory distress syndrome (ARDS) without detectable viremia, which may require a combination of IVIG with steroids, and cyclosporin A or etoposide (163,164).…”

Section: Targeting Cytokine Storm By Immunotherapiesmentioning

confidence: 99%

Immunopathogenesis of Different Emerging Viral Infections: Evasion, Fatal Mechanism, and Prevention

Yang

2021

Front. Immunol.

View full text Add to dashboard Cite

Different emerging viral infections may emerge in different regions of the world and pose a global pandemic threat with high fatality. Clarification of the immunopathogenesis of different emerging viral infections can provide a plan for the crisis management and prevention of emerging infections. This perspective article describes how an emerging viral infection evolves from microbial mutation, zoonotic and/or vector-borne transmission that progresses to a fatal infection due to overt viremia, tissue-specific cytotropic damage or/and immunopathology. We classified immunopathogenesis of common emerging viral infections into 4 categories: 1) deficient immunity with disseminated viremia (e.g., Ebola); 2) pneumocytotropism with/without later hyperinflammation (e.g., COVID-19); 3) augmented immunopathology (e.g., Hanta); and 4) antibody-dependent enhancement of infection with altered immunity (e.g., Dengue). A practical guide to early blocking of viral evasion, limiting viral load and identifying the fatal mechanism of an emerging viral infection is provided to prevent and reduce the transmission, and to do rapid diagnoses followed by the early treatment of virus neutralization for reduction of morbidity and mortality of an emerging viral infection such as COVID-19.

show abstract

Section: Targeting Cytokine Storm By Immunotherapiesmentioning

confidence: 99%

Immunopathogenesis of Different Emerging Viral Infections: Evasion, Fatal Mechanism, and Prevention

Yang

2021

Front. Immunol.

View full text Add to dashboard Cite

show abstract

Influenza-Associated Hemophagocytic Syndrome in Adults: Case Report and Review

Cited by 1 publication

References 21 publications

Immunopathogenesis of Different Emerging Viral Infections: Evasion, Fatal Mechanism, and Prevention

Immunopathogenesis of Different Emerging Viral Infections: Evasion, Fatal Mechanism, and Prevention

Contact Info

Product

Resources

About