The article identifies the main pathologies found and estimates the economic losses generated in a slaughterhouse in the Thailand municipality, Pará, during the period from March 2010 to October 2014. 55,169 animals were slaughtered, with total economic losses of R$ 1,221,035.90 and ischemia was the most frequent lesion (41.86%). The most frequent condemnation organs were lungs (48.75%), kidneys (41.66%) and liver (3.61%), which produced economic loss of R$ 76,405.65 (6.26%). Tuberculosis was the main cause of carcass condemnation, responsible for R$ 872,783.64 of economic losses. The bovine tuberculosis control can begin in production, with examinations on the farm to slaughter lines, with careful carcass inspection, as advocated by the National Program for the Control and Eradication of Animal Brucellosis and Tuberculosis (PNCEBT), which increases disease control and minimizes condemnations and economic losses at slaughter.