Influence of triiodothyronine and growth hormone on growth of dwarf and normal chickens: Interactions of hormones and genotype

The influence of growth hormone and thyroxine on iodothyronine deiodinase activity in the liver, kidney and brown adipose tissue in hypophysectomized rats

“…After 11 days of T4 substitution, no body weight increase was observed in hypophysectomized rats. This is in agreement with findings of Bowen et al (19) and Glasscock & Nicoll (20). On the other hand, Bowen found that GH treatment alone did not increase weight in thyroidectomized chickens, whereas when T3 was added, the weight gain nor¬ malized.…”

“…In our study we found a marked weight gain after GH treatment alone, but in contrast to the experiment of Bowen, our rats still had a rem¬ nant thyroid production which may explain the conflicting results. When GH and T4 were admin¬ istered together, weight gains more than normal¬ ized, probably owing to a "catch-up" growth spurt, indicating that even though T4 did not by itself induce weight gain (except in the kidney, Table 1), the hormone elicits a permissive action on the GH effect, as suggested by others (19,21).…”

The influence of growth hormone and thyroxine on iodothyronine deiodinase activity in the liver, kidney and brown adipose tissue in hypophysectomized rats

“…After 11 days of T4 substitution, no body weight increase was observed in hypophysectomized rats. This is in agreement with findings of Bowen et al (19) and Glasscock & Nicoll (20). On the other hand, Bowen found that GH treatment alone did not increase weight in thyroidectomized chickens, whereas when T3 was added, the weight gain nor¬ malized.…”

“…In our study we found a marked weight gain after GH treatment alone, but in contrast to the experiment of Bowen, our rats still had a rem¬ nant thyroid production which may explain the conflicting results. When GH and T4 were admin¬ istered together, weight gains more than normal¬ ized, probably owing to a "catch-up" growth spurt, indicating that even though T4 did not by itself induce weight gain (except in the kidney, Table 1), the hormone elicits a permissive action on the GH effect, as suggested by others (19,21).…”

Physiological studies on the sex-linked dwarfism of the fowl: a review on the search for the gene's primary effect

“…This last point justified the simultaneous administration of GH in some experiments of T3 or T4 supplementation (Marsh et al, 1984a;Bowen et aL, 1987 Scanes et al, 1983;Stewart et al, 1984;Lauterio et al, 1986;Bowen et al, 1987). However, IGF-I plasma level was always found to be reduced by about 50% Huybrechts et al, 1985a;Bowen et al, 1987). These results clearly show a deficient synthesis of IGF-I in dwarf birds, which constitutes new information regarding the mutation.…”

Relationship between comb development, immune regulation, growth hormone, testosterone, and growth traits in Tianfu broilers

“…However, the negative correlation between comb size and carcass yield highlights the need for careful consideration of these trade-offs in poultry breeding programs ( Holt, et al, 2024 ). In hens, the correlation between GH levels and comb development, as well as slaughter ratio suggests that comb traits could serve as useful indicators of growth efficiency and reproductive potential ( Bowen, et al, 1987 ). Further studies should investigate the genetic and environmental factors influencing comb development to better understand its evolutionary and practical relevance in poultry production.…”

The influence of growth hormone and thyroxine on iodothyronine deiodinase activity in the liver, kidney and brown adipose tissue in hypophysectomized rats

“…After 11 days of T4 substitution, no body weight increase was observed in hypophysectomized rats. This is in agreement with findings of Bowen et al (19) and Glasscock & Nicoll (20). On the other hand, Bowen found that GH treatment alone did not increase weight in thyroidectomized chickens, whereas when T3 was added, the weight gain nor¬ malized.…”

“…In our study we found a marked weight gain after GH treatment alone, but in contrast to the experiment of Bowen, our rats still had a rem¬ nant thyroid production which may explain the conflicting results. When GH and T4 were admin¬ istered together, weight gains more than normal¬ ized, probably owing to a "catch-up" growth spurt, indicating that even though T4 did not by itself induce weight gain (except in the kidney, Table 1), the hormone elicits a permissive action on the GH effect, as suggested by others (19,21).…”

Physiological studies on the sex-linked dwarfism of the fowl: a review on the search for the gene's primary effect

“…This last point justified the simultaneous administration of GH in some experiments of T3 or T4 supplementation (Marsh et al, 1984a;Bowen et aL, 1987 Scanes et al, 1983;Stewart et al, 1984;Lauterio et al, 1986;Bowen et al, 1987). However, IGF-I plasma level was always found to be reduced by about 50% Huybrechts et al, 1985a;Bowen et al, 1987). These results clearly show a deficient synthesis of IGF-I in dwarf birds, which constitutes new information regarding the mutation.…”

Relationship between comb development, immune regulation, growth hormone, testosterone, and growth traits in Tianfu broilers

“…However, the negative correlation between comb size and carcass yield highlights the need for careful consideration of these trade-offs in poultry breeding programs ( Holt, et al, 2024 ). In hens, the correlation between GH levels and comb development, as well as slaughter ratio suggests that comb traits could serve as useful indicators of growth efficiency and reproductive potential ( Bowen, et al, 1987 ). Further studies should investigate the genetic and environmental factors influencing comb development to better understand its evolutionary and practical relevance in poultry production.…”

The influence of growth hormone and thyroxine on iodothyronine deiodinase activity in the liver, kidney and brown adipose tissue in hypophysectomized rats

“…After 11 days of T4 substitution, no body weight increase was observed in hypophysectomized rats. This is in agreement with findings of Bowen et al (19) and Glasscock & Nicoll (20). On the other hand, Bowen found that GH treatment alone did not increase weight in thyroidectomized chickens, whereas when T3 was added, the weight gain nor¬ malized.…”

“…In our study we found a marked weight gain after GH treatment alone, but in contrast to the experiment of Bowen, our rats still had a rem¬ nant thyroid production which may explain the conflicting results. When GH and T4 were admin¬ istered together, weight gains more than normal¬ ized, probably owing to a "catch-up" growth spurt, indicating that even though T4 did not by itself induce weight gain (except in the kidney, Table 1), the hormone elicits a permissive action on the GH effect, as suggested by others (19,21).…”

Physiological studies on the sex-linked dwarfism of the fowl: a review on the search for the gene's primary effect

“…This last point justified the simultaneous administration of GH in some experiments of T3 or T4 supplementation (Marsh et al, 1984a;Bowen et aL, 1987 Scanes et al, 1983;Stewart et al, 1984;Lauterio et al, 1986;Bowen et al, 1987). However, IGF-I plasma level was always found to be reduced by about 50% Huybrechts et al, 1985a;Bowen et al, 1987). These results clearly show a deficient synthesis of IGF-I in dwarf birds, which constitutes new information regarding the mutation.…”

Relationship between comb development, immune regulation, growth hormone, testosterone, and growth traits in Tianfu broilers

“…However, the negative correlation between comb size and carcass yield highlights the need for careful consideration of these trade-offs in poultry breeding programs ( Holt, et al, 2024 ). In hens, the correlation between GH levels and comb development, as well as slaughter ratio suggests that comb traits could serve as useful indicators of growth efficiency and reproductive potential ( Bowen, et al, 1987 ). Further studies should investigate the genetic and environmental factors influencing comb development to better understand its evolutionary and practical relevance in poultry production.…”