2021
DOI: 10.1039/d1tb00789k
|View full text |Cite
|
Sign up to set email alerts
|

Abstract: Severe liver disease is one of the most common causes of death globally. Currently, whole organ transplantation is the only therapeutic method for end-stage liver disease treatment, however, the need...

Help me understand this report

Search citation statements

Order By: Relevance

Paper Sections

Select...
1
1
1
1

Citation Types

0
18
0

Year Published

2022
2022
2023
2023

Publication Types

Select...
5
1

Relationship

2
4

Authors

Journals

citations
Cited by 14 publications
(18 citation statements)
references
References 90 publications
(126 reference statements)
0
18
0
Order By: Relevance
“…A recent study investigated fibrous mats, electrospun from PCL, to create scaffolds for a liver tissue-engineering application. 130 Human liver cells (HepG2) were cultured on scaffolds composed of ∼3 μm diameter fibers with microscale surface depression features (0.37 and 2 μm). The cell viability was influenced by the size of the surface depressions, and an expression of several major liver genes was also found to be modulated by the topographies.…”
Section: Scanning Probe Lithography (Spl)mentioning
confidence: 99%
See 1 more Smart Citation
“…A recent study investigated fibrous mats, electrospun from PCL, to create scaffolds for a liver tissue-engineering application. 130 Human liver cells (HepG2) were cultured on scaffolds composed of ∼3 μm diameter fibers with microscale surface depression features (0.37 and 2 μm). The cell viability was influenced by the size of the surface depressions, and an expression of several major liver genes was also found to be modulated by the topographies.…”
Section: Scanning Probe Lithography (Spl)mentioning
confidence: 99%
“…Cell morphology displayed a dependency on fiber orientation, with both cell lines adopting a spindle-like shape on the aligned patterns. A recent study investigated fibrous mats, electrospun from PCL, to create scaffolds for a liver tissue-engineering application . Human liver cells (HepG2) were cultured on scaffolds composed of ∼3 μm diameter fibers with microscale surface depression features (0.37 and 2 μm).…”
Section: Fabrication Of Micro- and Nanotopographic Surfaces For Cell ...mentioning
confidence: 99%
“…8A). 54 In addition, Slivac et al compared a synthetic polyester PCL with a natural ECM isolated from pig liver 55 (Fig. 8B-a).…”
Section: Methods Of Liver Tissue Culturementioning
confidence: 99%
“…Gao et al prepared electrospun PCL mats by using an electrospinning system. 54 A HepG2 cell suspension was inoculated onto the PCL scaffold. Results have shown that the morphology of the fiber can significantly affect the behavior and growth of cells, and the fiber arrangement can affect cell elongation and orientation.…”
Section: Polycaprolactone (Pcl)mentioning
confidence: 99%
See 1 more Smart Citation