Influence of sensitization to inhalative allergens on adenotonsillar disease

Hofmann, Thiemo; Lackner, Andreas Ian; Berghold, Andrea; Lang‐Loidolt, Doris

doi:10.1016/s0194-5998(03)00525-4

Cited by 8 publications

(5 citation statements)

References 17 publications

Supporting

Mentioning

Contrasting

Unclassified

Order By: Relevance

“…He also examines the influence of atopy on the adenoid hypertrophy and suggests that allergic rhinitis is an important risk factor for adenoid hypertrophy in children and in other study they examined the incidence of adenoid hypertrophy in allergic children and concluded that the risk of adenoid hypertrophy in allergic children hypersensitive to dust mites is greater only in them with allergic rhinitis [18,19]. Hofman et al studied the influence of IgE-mediated sensitization on adenotonsillar disease in children and showed 22.9% of adenotonsillecttomid children had positive Rast results to inhalative allergens [20].…”

Section: Discussionmentioning

confidence: 99%

Is there any correlation between allergy and adenotonsillar tissue hypertrophy?

Shabestari

Moghaddam

Ghaharri

2011

International Journal of Pediatric Otorhinolaryngology

View full text Add to dashboard Cite

Section: Discussionmentioning

confidence: 99%

Is there any correlation between allergy and adenotonsillar tissue hypertrophy?

Shabestari

Moghaddam

Ghaharri

2011

International Journal of Pediatric Otorhinolaryngology

View full text Add to dashboard Cite

“…Forty-two children (73.68%) had polysensitization and 15 children (26.32%) had single sensitization. Congruent with previous literature, polysensitization was found to be more common in children with ATH [3]. Because of the high polysensitization ratio and small size of our study group, we did not perform statistical analyses to determine which allergen is more eosinophilic.…”

Section: Discussionmentioning

confidence: 73%

“…Allergy is one of the most common inflammatory processes for the upper respiratory tract [1]. Despite the fact that the prevalence of adenotonsillar disease is reported as 21.2% and 22.9% in some studies [2,3] in children with allergic rhinitis (AR), Griffin et al [4] reported that the prevalence of AR is similar to age-matched controls.…”

Section: Introductionmentioning

confidence: 99%

Relationship between tissue and serum eosinophilia in children undergoing adeno-tonsillectomy with allergic rhinitis

2019

Turk J Med Sci

View full text Add to dashboard Cite

Background/aim: Previous reports suggested that allergic/eosinophilic inflammation affects the adenoid and tonsillar tissue. The aim of this study is to evaluate and compare the tissue and serum eosinophilia in children undergoing adenotonsillectomy with allergic rhinitis. Materials and methods: The clinical registers of 125 children undergoing adenoidectomy/tonsillectomy due to adenoid/tonsil hypertrophy were examined and reviewed retrospectively. Fifty-seven children with positive skin prick test and symptoms of allergic rhinitis were included in the study as the atopic group, whereas 68 children with no allergic symptoms and negative skin prick test were included as the nonatopic group. Consequently, the total immunoglobulin E level and the serum and tissue eosinophilia of the atopic and nonatopic groups were compared. Results: Serum eosinophilia in the atopic group was found to be significantly higher than in the nonatopic group (P = 0.045). A significantly higher eosinophil count was found in adenoid/tonsil tissue of the atopic group (P < 0.001, P = 0.023, respectively). However, no significant correlation between tissue and serum eosinophilia was found. Conclusion: The inconsistency between tissue and serum eosinophilia in atopic children would particularly indicate a role of local atopy in adenotonsillar hypertrophy. Further studies are needed to better understand the effect and usefulness of serum and tissue eosinophilia in children with allergic rhinitis.

show abstract

“…The presence of sensitization to inhalant allergens apparently alters the immunology of adenoid tissue. Children with adenotonsillar disease have improved general health and nasal symptoms after adenoidectomy, regardless of whether they are atopic or nonatopic 15 . Saito et al 4 found that asthma symptoms improved in 88% of asthmatic children, and 60% of the children were able to eliminate the use of all medications after adenoidectomy or adenotonsillectomy.…”

Section: Discussionmentioning

confidence: 99%