volume 9, issue 4, P1096-1129 2017
DOI: 10.18632/aging.101210
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Antigoni Z. Lalia, Surendra Dasari, Matthew M. Robinson, Hinnah Abid, Dawn M. Morse, Katherine A. Klaus, Ian R. Lanza

Abstract: Omega-3 polyunsaturated fatty acids (n3-PUFA) are recognized for their anti-inflammatory effects and may be beneficial in the context of sarcopenia. We determined the influence of n3-PUFA on muscle mitochondrial physiology and protein metabolism in older adults. Twelve young (18-35 years) and older (65-85 years) men and women were studied at baseline. Older adults were studied again following n3-PUFA supplementation (3.9g/day, 16 weeks). Muscle biopsies were used to evaluate respiratory capacity (high resoluti…

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