D Ligeiro, J E Fonseca, O Abade, I Abreu, M Cruz, P Nero, J Cavaleiro, J Teles, H Trindade, J M Caetano, J Branco
Abstract:The well-recognised susceptibility alleles to rheumatoid arthritis, HLA-DRB1*04, were associated with rheumatoid arthritis in Portuguese patients. The relatively rare DRB1*10 was also associated with rheumatoid arthritis, as was described previously in other southern European countries. Both groups were associated with high anti-CCP titres, reinforcing its relevance to disease onset.
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