volume 31, issue 11, P759-764 2016
DOI: 10.1590/s0102-865020160110000009
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Abstract: ABSTRACT PURPOSE:To analyze the influence of chlorpromazine on renal histology of rats submitted to ischemia and reperfusion injury. METHODS:Sixteen Wistar rats -split in two groups -have been used: control group, receiving 3 mg/kg isotonic saline solution through caudal vein, and, the chlorpromazine group, receiving 3 mg/kg-IV of such medication. The nephrectomy of the left kidney lower third was carried out; immediately, the test-drug was administrated. After 15 minutes of test-drug administration, the rena…

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