1992
DOI: 10.1097/00132586-199202000-00029
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Abstract: We have studied the effects of anaesthesia on atelectasis formation and gas exchange in 45 patients of both sexes, smokers and nonsmokers, aged 23-69 yr. None of the patients showed clinical signs of pulmonary disease, and preoperative spirometry was normal. In the awake patient, partial pressure of arterial oxygen (Pa 0 J decreased with increasing age (P < 0.001) and the alveolar-arterial oxygen partial pressure difference (PA 02-Pa 0 J increased with age (P < 0.001). Shunt, assessed by the multiple inert gas… Show more

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Cited by 46 publications
(57 citation statements)
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“…As discussed above, atelectasis may be a less important cause of intraoperative hypoxemia during general anesthesia in elderly patients, 46 however, in elderly obese patients atelectasis may play a significant role in deterioration of postoperative oxygenation. 76 There has been considerable recent interest in maneuvers designed to recruit atelectatic lung regions.…”
Section: Airway and Ventilatory Managementmentioning
confidence: 98%
See 1 more Smart Citation
“…As discussed above, atelectasis may be a less important cause of intraoperative hypoxemia during general anesthesia in elderly patients, 46 however, in elderly obese patients atelectasis may play a significant role in deterioration of postoperative oxygenation. 76 There has been considerable recent interest in maneuvers designed to recruit atelectatic lung regions.…”
Section: Airway and Ventilatory Managementmentioning
confidence: 98%
“…For example, atelectasis in dependent lung regions usually develops after induction of anesthesia. However, Gunnarsson et al 46 found that atelectasis is not a prominent feature in elderly patients with healthy lungs during general anesthesia. Similarly, elderly patients with chronic obstructive pulmonary disease tend to show, at least initially following induction of anesthesia, less formation of atelectasis and less shunting compared with normal patients, due to their chronic lung hyperinflation.…”
Section: Mechanisms Of Postoperative Pulmonary Complicationsmentioning
confidence: 99%
“…Os diferentes mecanismos do sistema respiratório e a hipóxia encontrados nesses pacientes podem ser consequência da redução do volume pulmonar causada pela alta pressão intraabdominal (PELOSI et al, 1997). A formação de áreas de colapso alveolar pode ser encontrada em todas as idades (GUNNARSSON et al, 1991).…”
Section: Fatores Relacionados a áReas De Atelectasiaunclassified
“…Esses autores observaram sucessiva diminuição da complacência do sistema respiratório e coincidente redução da oxigenação arterial em humanos e animais anestesiados, fato interpretado como formação de atelectasia, a qual pode ser encontrada em diferentes níveis de acordo com a área pulmonar, existindo correlação entre a presença de shunt e a área de colapso pulmonar (BRISMAR et al, 1985;GUNNARSSON et al, 1991).…”
Section: Introductionunclassified
“…Возраст также является од ним из широко обсуждаемых пре дикторов снижения PaO 2 /FiO 2 в хо де оперативного вмешательства [3,25]. При многофакторном анализе установлено, что у пожилых паци ентов послеоперационная оксигени рующая функция легких, главным образом, зависит от дооперационно го состояния дыхательной системы [2].…”
Section: результаты и обсуждениеunclassified