2019
DOI: 10.1155/2019/2340725
|View full text |Cite
|
Sign up to set email alerts
|

Abstract: Burns are lesions in which the thermal energy of the causative agent transfers heat to the surface of the body, causing superficial or deep damage to the skin with protein denaturation in cells and biochemical maladjustments, which delay and disrupt the cicatricial process, increasing the chances of functional and aesthetic sequelae. This study evaluates the influence of adipose tissue-derived stem cells (ADSCs) on burn healing in terms of the size of the cicatricial space and quantified measures of collagen d… Show more

Help me understand this report

Search citation statements

Order By: Relevance

Paper Sections

Select...
3
1
1

Citation Types

2
31
0
3

Year Published

2019
2019
2023
2023

Publication Types

Select...
7
1

Relationship

0
8

Authors

Journals

citations
Cited by 44 publications
(36 citation statements)
references
References 23 publications
2
31
0
3
Order By: Relevance
“…Similar to our findings after creating burn injuries, a significant change in size of the burn wound was noted after transplantation of ADSCs (84.9%) in comparison with the control group (69.7%) . Franck et al reported a statistically significant decrease in the burn size with transplanted ADSCs (40.44%) when compared with the control group (32.26%) . In porcine model with contact burns using allogeneic MSCs with a fibrin matrix, a statistically reduced burn wound size was noted …”
Section: Discussionsupporting
confidence: 88%
See 1 more Smart Citation
“…Similar to our findings after creating burn injuries, a significant change in size of the burn wound was noted after transplantation of ADSCs (84.9%) in comparison with the control group (69.7%) . Franck et al reported a statistically significant decrease in the burn size with transplanted ADSCs (40.44%) when compared with the control group (32.26%) . In porcine model with contact burns using allogeneic MSCs with a fibrin matrix, a statistically reduced burn wound size was noted …”
Section: Discussionsupporting
confidence: 88%
“…Burn injury is characterized by destruction of skin structures, functions, and loss of progenitor cell populations that are necessary for regeneration and restoration of the skin. Burn wounds can delay and disrupt the cicatricial processes, and increase the chances of functional and aesthetic sequelae and are responsible for formation of scar and keloid due to scar contracture and uncontrollable proliferation of scar tissue …”
Section: Introductionmentioning
confidence: 99%
“…Fourteen studies [ 16 , 28 , 29 , 37 39 , 41 , 44 50 ] used rats, six studies [ 17 , 30 , 40 , 42 , 43 , 51 ] used mice, and two studies [ 36 , 52 ] used minipigs. A total of 10 studies were conducted in China [ 29 , 30 , 37 , 39 , 40 , 43 , 47 49 , 51 ], 3 studies in Brazil [ 16 , 28 , 41 ], 3 studies in the USA [ 36 , 42 , 52 ], and 2 studies in Iran [ 38 , 45 ], whereas the remaining 4 were conducted in Pakistan [ 46 ], Egypt [ 44 ], Turkey [ 50 ], and Canada [ 17 ], respectively. Four studies [ 40 , 43 , 48 , 51 ] did not report burn degree and two [ 38 , 45 ] used second-degree burns, while the others used third-degree.…”
Section: Resultsmentioning
confidence: 99%
“…Subsequently, the formation of scar and contracture will lead to considerable decrease of joint activity, and even the loss of function [ 14 ]. Various healing drugs including DNA [ 15 ], stem cells [ 16 , 17 ], growth factors [ 18 , 19 ], and siRNA [ 20 ] have been pursued to promote burn wound repair and regeneration. Although there are various treatment options, there is no consensus yet on the best treatment for severe burns such as deep partial-thickness and full-thickness burns.…”
Section: Introductionmentioning
confidence: 99%
“…In addition to the direct therapeutic effects of stem cell therapy via stem cell differentiation, stem cells indirectly accelerate tissue repair by enhancing the secretion of vascular endothelial cytokines such as CXCR4, MMP2/9, VEGF-α, and FGF2, which induce endothelial cell migration and proliferation into the transplantation site, leading to provided a suitable niche environment for the transplanted cells and enhanced AGING healing [9][10][11]. Human adipose derived stem cells (hADSCs) are important sources of adult stem cells that are known to contribute to angiogenesis, osteogenesis, and wound healing [12][13][14][15]. Compared with bone marrow-derived stem cells (BMSCs), hADSCs are favored in stem cell therapy for their advantages in terms of expansion ability, easy of isolation, and survival rate during culturing.…”
Section: Introductionmentioning
confidence: 99%