Annu. Rev. Immunol. volume 29, issue 1, P415-445 2011 DOI: 10.1146/annurev-immunol-031210-101322
|
Share
Margaret F. Gregor, Gökhan S. Hotamisligil
Abstract:

The modern rise in obesity and its strong association with insulin resistance and type 2 diabetes have elicited interest in the underlying mechanisms of these pathologies. The discovery that obesity itself results in an inflammatory state in metabolic tissues ushered in a research field that examines the inflammatory mechanisms in obesity. Here, we summarize the unique features of this metabolic inflammatory state, termed metaflammation and defined as low-grade, chronic inflammation orchestrated by metabol…

x
Citation Types
51
1,949
1
Paper Sections
0
0
0
0
0
Publication Types
0
0
0
0
Relationship beta
0
0