Inflammatory, immune-mediated adverse reactions related to soft tissue dermal fillers

Alijotas‐Reig, Jaume; Fernández‐Figueras, María Teresa; Puig, L.

doi:10.1016/j.semarthrit.2013.02.001

Cited by 119 publications

(116 citation statements)

References 177 publications

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“…) or rarely, systemic reactions (Alijotas‐Reig et al . ). In some case reports, an inflammatory reaction is documented many years after the dermal filler has been administered (Sanchis‐Bielsa et al .…”

Section: Resultsmentioning

confidence: 97%

The injecting use of image and performance-enhancing drugs (IPED) in the general population: a systematic review

Brennan

Wells

Hout

2016

Health Soc Care Community

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Injecting use of image and performance-enhancing drugs (IPED) in the general population is a public health concern. A wide and varied range of IPED are now easily accessible to all through the online market. A comprehensive literature review was undertaken according to Critical Appraisal Skills Programme (CASP) guidelines for systematic review, to identify the relevant literature. No date restrictions were placed on the database search in the case of human growth hormone melanotan I and II, and oil and cosmetic injectables. In the case of anabolic androgenic steroids search dates were restricted to January 2014-2015. Publications not in English and with a lack of specificity to the topic were excluded. The review yielded 133 relevant quantitative and qualitative papers, clinical trials, clinical case presentations and editorials/reports. Findings were examined/reviewed under emergent themes which identified/measured extent of use, user profiling, sourcing, product endorsement, risk behaviours and health outcomes in users. Motivation for IPED use may be grounded in appearance, pursuit of health and youth, and body image disturbance. IPED users can practice moderated use, with pathological use linked to high-risk behaviours, which may be normalised within IPED communities. Many IPED trajectories and pathways of use are not scientifically documented. Much of this information may be available online in IPED specific discussion forums, an underutilised setting for research, where uncensored discourse takes place among users. This review underscores the need for future internet and clinical research to investigate prevalence and patterns of injecting use, and to map health outcomes in IPED users. This paper provides community-based clinical practice and health promotion services with a detailed examination and analysis of the injecting use of IPED, highlighting the patterns of this public health issue. It serves to disseminate updated publication information to health and social policy makers and those in health service practice who are involved in harm reduction intervention.

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Section: Resultsmentioning

confidence: 97%

The injecting use of image and performance-enhancing drugs (IPED) in the general population: a systematic review

Brennan

Wells

Hout

2016

Health Soc Care Community

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“…More detailed discussions about complications after soft-tissue augmentation have been published elsewhere. 32,51,54,64,70,71 Based on extensive clinical experience, the Asia-Pacific Consensus recommendations are the first developed specifically for the use of fillers in Asian populations and are intended for injectors worldwide who wish to better familiarize themselves with Asian indications and injection procedures for optimal outcomes with a high level of safety when using cohesive polydensified matrix/hyaluronic acid and/or calcium hydroxylapatite.…”

Section: Discussionmentioning

confidence: 99%

“…18,64 In general, all fillers are capable of stimulating a foreign-body reaction, which results in the formation of mature fibrous tissue around the implant. 18 Some of these reactions may indicate the presence of a biofilm-quiescent infection by bacteria leading to the formation of a densely packed community of microorganisms encapsulated by a protective matrix that allows them to irreversibly adhere to living or inert surfaces.…”

Section: Inflammatory Nodulesmentioning

confidence: 99%

Consensus Recommendations for Optimal Augmentation of the Asian Face with Hyaluronic Acid and Calcium Hydroxylapatite Fillers

Rho

Yao

Chao

et al. 2015

Plastic and Reconstructive Surgery

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“…Granuloma formation is considered the most common complication of dermal fillers [8]. Although foreign body granuloma represented the standard reaction of filler injection, other histologic responses could be observed such as chronic inflammation, fibrosis, fat necrosis, and panniculitis [9,10].…”

Section: Discussionmentioning

confidence: 99%

Dermal filler complications: a clinicopathologic study with a spectrum of histologic reaction patterns

El‐Khalawany

Fawzy

Saied

et al. 2015

Annals of Diagnostic Pathology

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Inflammatory, immune-mediated adverse reactions related to soft tissue dermal fillers

Cited by 119 publications

References 177 publications

The injecting use of image and performance-enhancing drugs (IPED) in the general population: a systematic review

The injecting use of image and performance-enhancing drugs (IPED) in the general population: a systematic review

Consensus Recommendations for Optimal Augmentation of the Asian Face with Hyaluronic Acid and Calcium Hydroxylapatite Fillers

Dermal filler complications: a clinicopathologic study with a spectrum of histologic reaction patterns

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