“…Inflammatory BC is also included in LABC [ 4 , 32 ]. Breast tumours larger than 5 cm without regional lymphadenopathy have also been included as LABC by some authors (T3N0M0) [ 33 – 36 ].” In the treatment of LABC, neoadjuvant therapy is usually recommended to downstage the disease, followed by timely surgery, radiotherapy, and systemic therapy following the surgery [ 24 , 26 , 37 , 38 ]. The purpose of NACT is to ameliorate surgical options and to assess treatment response in the breast.…”