Inflammatory bowel disease versus irritable bowel syndrome: a hospital‐based, case‐control study of disease impact on quality of life

Pace, F.; Molteni, Paola; Bollani, S.; Sarzi-Puttini, Piercarlo; Stockbrügger, Reinhold W.; Porro, G. Bianchi; Drossman, Douglas A.

doi:10.1080/00365520310004524

Cited by 116 publications

(91 citation statements)

References 48 publications

Supporting

Mentioning

Contrasting

Unclassified

Order By: Relevance

“…2 However, only one-third of those who suffer from IBS-like symptoms see a physician, the actual prevalence may be much higher. IBS impairs the quality of life in patients to a similar degree as in patients with inflammatory bowel diseases 3 and the impairment is proportional to the severity of the symptoms experienced by the patient. 4 IBS is a heterogeneous entity with etiology comprising of multiple factors such as inflammation, neuroimmune interactions, 5 gut microbiota, 6 environmental pollution, 7 and abnormal gut-brain axis.…”

Section: Introductionmentioning

confidence: 99%

Targeting Histamine Receptors in Irritable Bowel Syndrome: A Critical Appraisal

Fabisiak

Włodarczyk

Fabisiak

et al. 2017

J Neurogastroenterol Motil

View full text Add to dashboard Cite

Irritable bowel syndrome is a group of functional gastrointestinal disorders with not yet fully clarified etiology. Recent evidence suggesting that mast cells may play a central role in the pathogenesis of irritable bowel syndrome paves the way for agents targeting histamine receptors as a potential therapeutic option in clinical treatment. In this review, the role of histamine and histamine receptors is debated. Moreover, the clinical evidence of anti-histamine therapeutics in irritable bowel syndrome is discussed.

show abstract

Section: Introductionmentioning

confidence: 99%

Targeting Histamine Receptors in Irritable Bowel Syndrome: A Critical Appraisal

Fabisiak

Włodarczyk

Fabisiak

et al. 2017

J Neurogastroenterol Motil

View full text Add to dashboard Cite

show abstract

“…An increased stress appears to facilitate disease reactivation. IBDs can be affected by stress 9,10 . Stress modulates colonic motility 11 and it influences the endocrine and immune system which are mediators of the inflammatory process.…”

Section: Stress and Inflammatory Bowel Diseasesmentioning

confidence: 99%

“…IBS and IBDs have significantly greater stress burdens than controls 10 and higher levels of psychiatric distress, alexithymia and somatosensory amplification 14 . Unlike short-term stress, the perception of chronic stress appears to increase the risk of exacerbation of ulcerative colitis 13 .…”

mentioning

confidence: 99%

Psychological Aspects and Psychotherapy of Inflammatory Bowel Diseases and Irritable Bowel Syndrome in Children

Praško¹,

Jelenová²,

Mihál³

2010

Biomed Pap Med Fac Univ Palacky Olomouc Czech Repub

View full text Add to dashboard Cite

“…Over 50% of IBS subjects-consulters [33] and non-consulters alike [34] report that stressful events precipitate or worsen their symptoms. While some previous studies have observed that IBS subjects experience a slightly greater number of stressful life events than do controls or patients with other digestive disease [35,36] , other studies have observed no differences in this regard [6,37] . In a prospective study, Levy et al [38] failed to find differences between IBS subjects and controls in the number of positive or negative daily events, but self-reported daily stress was higher among IBS subjects.…”

Section: Discussionmentioning

confidence: 70%

Constructive thinking, rational intelligence and irritable bowel syndrome

Rey¹,

Ortega²,

Alonso³

et al. 2009

WJG

View full text Add to dashboard Cite

AIM:To evaluate rational and experiential intelligence in irritable bowel syndrome (IBS) sufferers. METHODS:We recruited 100 subjects with IBS as per Rome Ⅱ criteria (50 consulters and 50 non-consulters) and 100 healthy controls, matched by age, sex and educational level. Cases and controls completed a clinical questionnaire (including symptom characteristics and medical consultation) and the following tests: rationalintelligence (Wechsler Adult Intelligence Scale, 3rd edition); experiential-intelligence (Constructive Thinking Inventory); personality (NEO personality inventory); psychopathology (MMPI-2), anxiety (state-trait anxiety inventory) and life events (social readjustment rating scale). Analysis of variance was used to compare the test results of IBS-sufferers and controls, and a logistic regression model was then constructed and adjusted for age, sex and educational level to evaluate any possible association with IBS. RESULTS:No differences were found between IBS cases and controls in terms of IQ (102.0 ± 10.8 vs 102.8 ± 12.6), but IBS sufferers scored significantly lower in global constructive thinking (43.7 ± 9.4 vs 49.6 ± 9.7). In the logistic regression model, global constructive thinking score was independently linked to suffering from IBS ], without significant OR for total IQ. CONCLUSION:IBS subjects do not show lower rational intelligence than controls, but lower experiential intelligence is nevertheless associated with IBS.

show abstract

Inflammatory bowel disease versus irritable bowel syndrome: a hospital‐based, case‐control study of disease impact on quality of life

Abstract: Our study supports the notion that, at least in referral centres, patients with IBS show health-related quality of life, psychological distress and recent occurrence of stressful life events of severity at least comparable with age-matched IBD patients.

Cited by 116 publications

References 48 publications

Targeting Histamine Receptors in Irritable Bowel Syndrome: A Critical Appraisal

Targeting Histamine Receptors in Irritable Bowel Syndrome: A Critical Appraisal

Psychological Aspects and Psychotherapy of Inflammatory Bowel Diseases and Irritable Bowel Syndrome in Children

Constructive thinking, rational intelligence and irritable bowel syndrome

Contact Info

Product

Resources

About