volume 48, issue 12, P1115-1121 2015
DOI: 10.1590/1414-431x20154487
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Abstract: AbstractThe levels of serum inflammatory cytokines and the activation of nuclear factor kappa B (NF-kB) and hypoxia inducible factor-1a (HIF-1a) in heart tissues in response to different frequencies of intermittent hypoxia (IH) and the antioxidant tempol were evaluated. Wistar rats (64 males, 200-220 g) were randomly divided into 6 experimental groups and 2 control groups. Four groups were exposed to IH 10, 20, 30, or 40 times/h. The other 2 experimental groups were challenged with IH (30 times/h) plus tempol…

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