Inflammation in Wound Healing and Pathological Scarring

Hong, Yi-Kai; Chang, Yi-Han; Lin, Yuh Jyh; Chen, Brandon; Guevara, Bryan Edgar K; Hsu, Chao‐Kai

doi:10.1089/wound.2021.0161

Cited by 24 publications

(3 citation statements)

References 116 publications

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“…Therefore, the epidermal regeneration must first dissolve the scab, because the dryness of the scab is not conducive to the growth of bacteria; it has a certain protective effect on the wound. However, if the scab obstructs the drainage of exudate and makes the infection worse, it is not conducive to healing 20–23 …”

Section: Methodsmentioning

confidence: 99%

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Analysis of risk factors affecting wound healing and wound infection after meningioma resection

Wang,

Shou,

Gao

et al. 2024

International Wound Journal

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To analyse the risk factors affecting wound healing and infection after spinal meningioma resection surgery. The surgical incision healing of 137 patients who underwent spinal meningioma resection at our hospital from January 2021 to January 2024 was analysed. The data collected included physical examination findings, haematological and biochemical measurements, and various scales assessed upon admission and after surgery. These data were then analysed. The surgical wound healing, infection and postoperative complications were statistically analysed. Multiple logistic regression analysis method was used to conduct risk factor analysis on corresponding indicators; the odds ratio and p value of 95% confidence interval were calculated. Factors such as age and smoking history were significantly negatively correlated with wound healing after meningioma resection (odds ratio < 1.000, p < 0.05), while preoperative albumin and platelet count were significantly positively correlated with wound healing (odds ratio > 1.000, p < 0.05). Age, WHO Meningioma Grading, preoperative albumin and preoperative platelet were significantly negatively correlated with wound infection after meningioma resection (odds ratio < 1.000, p < 0.05). The history of virus infection and history of neurological disorders were significantly positively correlated with wound infection (odds ratio > 1.000, p < 0.05). The influence of each factor is different. Age, smoking history, WHO Meningioma Grading, preoperative albumin, preoperative platelets, history of virus infection and history of neurological disorders had the greatest influence on wound healing and infection after meningioma resection.

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Section: Methodsmentioning

confidence: 99%

“…However, if the scab obstructs the drainage of exudate and makes the infection worse, it is not conducive to healing. [20][21][22][23]…”

Section: Staging Of Surgical Wound Healingmentioning

confidence: 99%

Analysis of risk factors affecting wound healing and wound infection after meningioma resection

Wang,

Shou,

Gao

et al. 2024

International Wound Journal

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“…The second phase of wound healing, inflammation, is crucial for eliminating harmful bacteria and debris [48]. While inflammation is necessary for proper wound repair, it is important to control it through dressings [49].…”

Section: Inflammation Control Using Hydrogel Dressingsmentioning

confidence: 99%

Functional hydrogel dressings for wound management: a comprehensive review

Fu,

Zheng,

Wen

et al. 2023

Mater. Res. Express

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Hydrogels have gained significant attention as wound dressings due to their potential for rapid healing. Researchers have actively explored a range of techniques for antimicrobial applications, including incorporating drug payloads, utilizing inorganic nanometals, and harnessing the properties of natural cationic polymers. In terms of hemostasis and coagulation promotion, techniques such as drug delivery, adhesive physical hemostasis, and adhesive functional groups have been studied. To control inflammation, researchers have investigated the application of natural antioxidants and antioxidant functional groups, which have demonstrated anti-inflammatory effects. Furthermore, the smart responsiveness of hydrogel wound dressings to pH, temperature, and light has been explored. This review presents a summary of the research progress and application prospects in these areas and offers an outlook on the future development direction of hydrogel wound dressings.

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