Infiltrated blue-gray plaques in a patient with leukemia. Chloroma (granulocytic sarcoma)

Metastatic Tumors to the Nail Unit: Subungual Metastases

“…52 Cancer-related skin lesions originating from an internal malignancy may present as cutaneous metastases in patients with solid tumors or infiltration of the skin by leukemic cells (leukemia cutis) in patients with hematologic malignancies. 100 Lymphoma cutis occurs in the setting of primary lymphomas of the skin or as a secondary site of dissemination. 101,102 The cancers that most frequently metastasize to the skin are those that occur most commonly in the general population: in men these include carcinoma of the lung and colon, melanoma, and oral cavity tumors; in women these include carcinoma of the breast, colon, lung, and ovary and melanoma.…”

Metastatic Tumors to the Nail Unit: Subungual Metastases

“…Cancer‐related skin lesions originating from an internal malignancy may present as cutaneous metastases in patients with solid tumors or infiltration of the skin by leukemic cells (leukemia cutis) in patients with hematologic malignancies 100 . Lymphoma cutis occurs in the setting of primary lymphomas of the skin or as a secondary site of dissemination 101,102 .…”

Leonine facies associated with eyebrow loss

“…The disorders associated with leonine facies accompanied by eyebrow loss, similar to that observed in Ravic-Nikolic et al's 1 patient, is limited and includes granulomatous conditions, infectious diseases, inherited syndromes, malignancy (such as lymphoma and leukemia cutis), reactive dermatoses, and other conditions ( Table 1). [1][2][3][4][5] An important clinical feature regarding the loss of eyebrows associated with leonine facies-related conditions is that the eyebrow disappearance is usually permanent-even after successful treatment of the underlying disorder.…”