Infeksi Biofilm Bakterial

Abstract

Biofilm is the unity of microbial cell surface surrounded by a matrix of extracellular polymeric substances (EPS). Bacteria composing the biofilm are heterogeneous in space and time. This biofilm continues to grow influenced by internal and external processes. Moreover, biofilm can be found on the surface of medical devices, as well as in bacterial endocarditis and cystic fibrosis. Biofilm that is already formed can lead to antibiotic resistance.Keywords: infections, bacterial biofilm, antibiotic resistance Abstrak: Biofilm merupakan kesatuan dari permukaan sel mikroba yang dilingkupi oleh matriks substansi polimerik ekstraseluler. Bakteri yag menyusun biofilm bersifat heterogen dalam ruang dan waktu. Biofilm terus berkembang yang dipengaruhi oleh proses internal dan eksternal. Biofilm dapat ditemukan pada permukaan alat-alat medis, endokarditis bakterial, dan kistik fibrosis. Biofilm yang telah terbentuk dapat menyebabkan resistensi antibiotik. Kata kunci: infeksi, biofilm bakterial, resistensi antibiotik

The Efficacy of Photodynamic Inactivation with Laser Diode on Staphylococcus aureus Biofilm with Various Ages of Biofilm

“…6. 21 (6) Statistical analysis was performed with the help of IBM SPSS 21 (Statistical Package and Service Solutions) software using a two way ANOVA test with equal variances assumed tuckey P<0.05.…”

“… 4 , 5 The National Institutes of Health states that more than 65% of the microbial infections were related to biofilms. 6 …”

“…Each bacterium produces different EPS so that each biofilm has different chemical and physical properties. 6 The formation of biofilms is divided into several stages, including the attachment to a surface, the production phase of Extracellular Polymeric Substances (EPS), the initial growth stage of the biofilm layer, the maturation stage of the biofilm layer, and the detachment or release of bacterial cells from the biofilm. 4 The formation of biofilms starts from free-living planktonic cells that attach to a surface.…”

“…4,5 The National Institutes of Health states that more than 65% of the microbial infections were related to biofilms. 6 EPS covers about 50% to 90% of the total biofilm forming components, and 15% of the volume is a collection of microorganisms. 7 EPS is a polysaccharide produced by bacteria themselves, that is able to protect the bacteria and has an adhesive function between bacteria.…”

Antibacterial of Cinnamon Bark (Cinnamomum burmannii) Essential Oil Against Methicillin-Resistant Staphylococcus aureus

“…Perkembangan biofilm dipengaruhi oleh proses internal dan eksternal. Biofilm yang telah terbentuk dapat menimbulkan sifat resistensi bakteri terhadap suatu antibiotik (Homenta, 2016 Gambar 1. Zona hambat minyak atsiri kayu manis terhadap MRSA yang diisolasi dari susu sapi atsiri yang digunakan, namun mekanisme lebih lanjut mengenai aktivitas penghambatan pembentukan biofilm ini tidak sepenuhnya diketahui (Jia et al, 2011).…”