Infection of the Cavernous Sinus Caused by Candida auris

Abstract

Recently, strains of Candida, a fungus resistant to antifungal agents, have increased. Candida auris (C. auris) infection is a serious global health threat [1]. Healthcare facilities in several countries have reported severe C. auris infections among inpatients [2]. C. auris is often resistant to common antifungal agents, causing difficulty in treatment [1,2].Cavernous sinus infection is a rare, potentially lifethreatening condition that requires prompt treatment and is associated with a high mortality rate despite antimicrobial therapy [3]. Herein, we report the case of a 60-year-old woman diagnosed with a cavernous sinus infection and pachymeningitis caused by C. auris. We successfully administered triple antifungal combination therapy, and the patient fully recovered from the severe infection. To the best of our knowledge, there have been no previous reports of cavernous sinus infections caused by C. auris in South Korea. Therefore, we report this case and discuss the use of combination antifungal therapy to treat C. auris.