Infection Management

DeSimone, Daniel C.; Sohail, M. Rizwan

doi:10.1016/j.ccep.2018.04.002

Cited by 8 publications

(9 citation statements)

References 32 publications

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“…Further, the major complication rate related to the procedure within 7 days after the procedure was similar between the left axilla and control groups (left ante- 134±62.4 vs. 114±33.5 min, p = .11), respectively. Because the procedure duration plays a key role in terms of procedure related CIED infections, 13,14 it is important to keep the procedure time similar to that of the previously performed implantation method. In fact, our study demonstrated that no device infections occurred in the left axilla group during the follow up.…”

Section: Discussionmentioning

confidence: 99%

Safety and feasibility of implanting a transvenous implantable cardioverter defibrillator (TV‐ICD) in the left axilla

Enomoto

Noro

Toyoda

et al. 2021

Pacing Clinical Electrophis

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Background: Transvenous implantable cardioverter defibrillator (TV-ICD) systems are commonly implanted in the left anterior chest because of an easier implantation and better defibrillation threshold. This study aimed to evaluate the safety and feasibility of left axillary implantations of TV-ICD systems. Methods:We performed left axillary TV-ICD implantations and compared that to the major complication rate and operation time of the conventional TV-ICD implantation site (left anterior chest). The electrical parameter trends were also assessed in the left axilla group.Results: Seventy-six consecutive patients were evaluated for the analysis. Thirty-one patients had their system implanted in the left axilla and the reasons for the implantations included 29 patients for cosmetic reasons and two for post-infection conditions. The operation time and major complication rate were similar between the two groups (left anterior chest vs. left axilla: 134±62.4 min vs. 114±33.5 min, p = .11, 1/45 patient, 2.2% [pocket hematoma] vs. 1/31 patient, 3.2% [lead dislodgement], p = .77).During the follow up period (4.9±2.3years), no lead interruptions were observed in either group. The electrical lead parameters at the time of the implantation and follow up were similar in the study group (R wave sensing 20.8±33.4 vs. 11.2±7.42 mv, p = .34; lead impedance 464±64.7 vs. 418±135ohm, p = .22; pacing threshold [at 0.4 ms] 1.0±0.76 vs. 1.21±0.93V, p = .49). Conclusion:TV-ICD implantations in the left axilla were performed safely without increasing the operation time as compared to the conventional ICD implantation site.ICD implantations in the left axilla are an alternative in those not suitable for implanting TV-ICDs in the conventional implantation site.

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Section: Discussionmentioning

confidence: 99%

Safety and feasibility of implanting a transvenous implantable cardioverter defibrillator (TV‐ICD) in the left axilla

Enomoto

Noro

Toyoda

et al. 2021

Pacing Clinical Electrophis

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“…Por sua vez, as infecções sistêmicas podem ocorrer na ausência de processo infeccioso da loja do gerador. Esse fato torna o diagnóstico mais desafiador e deve haver alta suspeição quando há febre, calafrios, sudorese noturna e fenômenos embólicos sépticos [2][3][4][5][6][7] . O diagnóstico é baseado nos critérios internacionais de infecção de DCEI de 2019, que incluem aspectos microbiológicos, radiológicos e clínicos 2 .…”

Section: Discussionunclassified

Infecção de loja de cardioversor-desfibrilador implantável (CDI) por klebsiella sp. Carbapenem-resistente

Gâmbaro

Moura

Reis

et al. 2021

Medicina (Ribeirão Preto)

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As infecções associadas aos Dispositivos Cardíacos Eletrônicos Implantáveis (DCEI) apresentam uma incidência de até 3,4% e notável impacto na morbidade e mortalidade dos pacientes. As bactérias Gram-positivas, especialmente do gênero Staphylococcus sp. representam 60-70% dos agentes isolados. Por sua vez, as Gram-negativas correspondem até 9% dos casos. Relatamos uma infecção de loja de gerador de Cardioversor-desfibrilador implantável (CDI) por uma Klebsiella sp. resistente aos carbapenêmicos, em um paciente masculino jovem, cujo desafiador diagnóstico de certeza desse caso somente foi possível após exploração cirúrgica e cultura do material da loja do CDI, haja vista a apresentação clínica oligossintomática. Embora já descritas, Klebsiella sp. são raras nesse contexto e em nosso conhecimento, esse é o primeiro relato de uma infecção de DCEI por uma enterobactéria resistente a carbapenêmico.

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“…Several cardiac conditions require additional non-device approaches as in the case of a congenital heart block, which cannot be treated using electronic pacemakers, or in the case of a contraindication to reimplantation before effective antibiosis is established. A congenital heart block and other congenital cardiac conditions could result in fetal death or stillbirth and, in most cases, require in utero pacing (Gutiérrez et al, 1989 ; DeSimone and Sohail, 2018 ; Manolis et al, 2020 ).…”

Section: Introductionmentioning

confidence: 99%

Bioengineering the Cardiac Conduction System: Advances in Cellular, Gene, and Tissue Engineering for Heart Rhythm Regeneration

Naumova

Iop

2021

Front. Bioeng. Biotechnol.

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Heart rhythm disturbances caused by different etiologies may affect pediatric and adult patients with life-threatening consequences. When pharmacological therapy is ineffective in treating the disturbances, the implantation of electronic devices to control and/or restore normal heart pacing is a unique clinical management option. Although these artificial devices are life-saving, they display many limitations; not least, they do not have any capability to adapt to somatic growth or respond to neuroautonomic physiological changes. A biological pacemaker could offer a new clinical solution for restoring heart rhythms in the conditions of disorder in the cardiac conduction system. Several experimental approaches, such as cell-based, gene-based approaches, and the combination of both, for the generation of biological pacemakers are currently established and widely studied. Pacemaker bioengineering is also emerging as a technology to regenerate nodal tissues. This review analyzes and summarizes the strategies applied so far for the development of biological pacemakers, and discusses current translational challenges toward the first-in-human clinical application.

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Infection Management

Cited by 8 publications

References 32 publications

Safety and feasibility of implanting a transvenous implantable cardioverter defibrillator (TV‐ICD) in the left axilla

Safety and feasibility of implanting a transvenous implantable cardioverter defibrillator (TV‐ICD) in the left axilla

Infecção de loja de cardioversor-desfibrilador implantável (CDI) por klebsiella sp. Carbapenem-resistente

Bioengineering the Cardiac Conduction System: Advances in Cellular, Gene, and Tissue Engineering for Heart Rhythm Regeneration

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