Inertial sensor based reference gait data for healthy subjects

Schwesig, René; Leuchte, S.; Fischer, David A.; Ullmann, Regina; Kluttig, Alexander

doi:10.1016/j.gaitpost.2011.02.023

Cited by 69 publications

(57 citation statements)

References 22 publications

(38 reference statements)

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“…The mean coefficient of variation values of PINP and CTX analyses were 3.7% and 1.7%, respectively. Evaluation of functional recovery included the measurements of walking speed using a validated gait analysis system (RehaWatch, Hasomed GmbH, Germany) . Subjects were asked to walk at a self‐selected comfortable walking speed along a 10‐m walkway, and the mean coefficient of variation of the repeated measurements was 4.7%.…”

Section: Methodsmentioning

confidence: 99%

“…Evaluation of functional recovery included the measurements of walking speed (48) using a validated gait analysis system (RehaWatch, Hasomed GmbH, Germany). (49) Subjects were asked to walk at a self-selected comfortable walking speed (48) along a 10-m walkway, and the mean coefficient of variation of the repeated measurements was 4.7%. Assessment of interindividual differences in daily walking activity was performed by means of digital pedometers (50) for 7 days.…”

Section: Exploratory and Safety Endpointsmentioning

confidence: 99%

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Effect of Denosumab on Femoral Periprosthetic BMD and Early Femoral Stem Subsidence in Postmenopausal Women Undergoing Cementless Total Hip Arthroplasty

et al. 2019

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Antiresorptive denosumab is known to improve the quality and strength of cortical bone in the proximal femurs of osteoporotic women, but its efficacy in preventing periprosthetic bone loss and reducing femoral stem migration has not been studied in women undergoing cementless total hip arthroplasty. We conducted a single‐center, randomized, double‐blinded, placebo‐controlled trial of 65 postmenopausal women with primary hip osteoarthritis and Dorr type A or B proximal femur anatomy. The patients randomly received subcutaneous injections of denosumab 60 mg or placebo once every 6 months for 12 months, starting 1 month before surgery. The primary endpoint was the change in bone mineral density (BMD) of the proximal femur (Gruen zone 7) at week 48, and the secondary endpoint was stem subsidence measured by radiostereometric analysis (RSA) at week 48. Exploratory endpoints included changes in BMDs of the contralateral hip, lumbar spine and distal radius, serum levels of bone turnover markers, walking speed, walking activity, patient‐reported outcome measures, and radiographic assessment of stem osseointegration. The participants underwent vertebral‐fracture assessment in an extension safety study at 3 years. Denosumab significantly decreased bone loss in the medial femoral neck (zone 7) and increased periprosthetic BMD in the greater trochanteric region (zone 1) and lesser trochanteric region (zone 6). Denosumab did not reduce temporary femoral stem migration. The migration occurred mainly during the settling period (0 to 12 weeks) after implantation of the prosthesis. All of the stems osseointegrated, as evaluated by RSA and radiographs. There were no intergroup differences in functional recovery. Discontinuation of denosumab did not lead to any adverse events. In conclusion, denosumab increased periprosthetic BMD in the clinically relevant regions of the proximal femur, but the treatment response was not associated with any reduction of initial stem migration. © 2019 The Authors. JBMR Plus published by Wiley Periodicals, Inc. on behalf of the American Society for Bone and Mineral Research.

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Section: Methodsmentioning

confidence: 99%

Section: Exploratory and Safety Endpointsmentioning

confidence: 99%

Effect of Denosumab on Femoral Periprosthetic BMD and Early Femoral Stem Subsidence in Postmenopausal Women Undergoing Cementless Total Hip Arthroplasty

et al. 2019

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“…A comprehensive description of both systems, including the information regarding reliability, validity, reference data and their value to measure falls risk, is available elsewhere. 17,18,[21][22][23][24][25] Data collection for each subject took approximately 20 minutes. During a follow-up period of 12 months, all falls were recorded by the caregivers at the nursing home in a standardized falls protocol.…”

Section: Methodsmentioning

confidence: 99%

Can falls be predicted with gait analytical and posturographic measurement systems? A prospective follow-up study in a nursing home population

et al. 2012

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“…These parameters were obtained through analysis of trunk accelerations, a technique considered robust and that exploits the fact that foot contacts with the ground cause distinct, rapid, and easily identifiable oscillations of the accelerometric signal (Kavanagh and Menz, 2008). Of note is that trunk accelerations have been demonstrated to be reliable in characterizing childrens' gait patterns (Brandes et al, 2006;Schwesig et al, 2011). Children were instructed to walk along an 8-m pathway (corresponding to $6-10 steps depending on a child's step length), at a self-selected speed and in the most natural manner possible.…”

Section: Gradementioning

confidence: 99%

Short-term effects of backpack carriage on plantar pressure and gait in schoolchildren

Pau

Mandaresu

Leban

et al. 2015

Journal of Electromyography and Kinesiology

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Inertial sensor based reference gait data for healthy subjects

Cited by 69 publications

References 22 publications

Effect of Denosumab on Femoral Periprosthetic BMD and Early Femoral Stem Subsidence in Postmenopausal Women Undergoing Cementless Total Hip Arthroplasty

Effect of Denosumab on Femoral Periprosthetic BMD and Early Femoral Stem Subsidence in Postmenopausal Women Undergoing Cementless Total Hip Arthroplasty

Can falls be predicted with gait analytical and posturographic measurement systems? A prospective follow-up study in a nursing home population

Short-term effects of backpack carriage on plantar pressure and gait in schoolchildren

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