Separation of fumaric acid from aqueous media with tridodecyl amine (TDA), which is a long chain aliphatic amine, was carried out at 298 K. Different categories of diluents, ketones (methyl iso butyl ketone (MIBK), 2-heptanone, and 2-octanone) and alcohols (isoamyl alcohol, 1-octanol, and 1-decanol) were used to dissolve TDA. Distribution coefficients (K D ), extraction efficiency (E), and loading factors (Z) were obtained as a function of experimental results. The most operative diluent was determined as heptan-2-one with the highest distribution coefficient (K D ) value of 26.00. In additional to experimental studies, the linear solvation energy relationship (LSER) modeling with included Hidebrand−Hansen solubility parameters was applied for alcoholic diluents. Predicted data by LSER gave good agreement with experimental data.