2008
DOI: 10.1016/j.aquatox.2008.07.009
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Induction of time-dependent oxidative stress and related transcriptional effects of perfluorododecanoic acid in zebrafish liver

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Cited by 174 publications
(66 citation statements)
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“…The results are in accordance with Jin et al (2010), Velisek et al (2011) and Xing et al (2012). The increase in malondialdehde following atrazine exposure may be attributed to the induction of reactive oxygen species (ROS), which enhance the oxidation of polyunsaturated fatty acids and lead to lipid peroxidation (Liu et al, 2008). Data are represented as means ± SE (n = 10).…”
Section: Resultssupporting
confidence: 69%
“…The results are in accordance with Jin et al (2010), Velisek et al (2011) and Xing et al (2012). The increase in malondialdehde following atrazine exposure may be attributed to the induction of reactive oxygen species (ROS), which enhance the oxidation of polyunsaturated fatty acids and lead to lipid peroxidation (Liu et al, 2008). Data are represented as means ± SE (n = 10).…”
Section: Resultssupporting
confidence: 69%
“…BCL2, which localizes to sites of free radical generation, functions as an apparent antioxidant against oxidative stress to prevent apoptosis (Hockenbery et al, 1993). Previous studies have indicated that the decreased mRNA levels of BCL2 are associated with enhanced oxidative damage (Liu et al, 2008). This finding further illuminates the depletion of the antioxidant potential after exposure to difenoconazole.…”
Section: Discussionmentioning
confidence: 89%
“…The increased levels of lipid peroxidation in fish liver in response to the exposure to the herbicides in this study suggest there is increase in the production of reactive oxygen species (ROS). Reactive Oxygen Species induction enhances the oxidation of polyunsaturated fatty acids which can end up in peroxidation of lipids (Valavanidis et al, 2006;Liu et al, 2008). Significant differences were noticed in malondialdehyde (MDA) levels in both concentration and time (Table 8).…”
Section: Discussionmentioning
confidence: 98%