Inducing Long Lasting B Cell and T Cell Immunity Against Multiple Variants of SARS‐CoV‐2 Through Mutant Bacteriophage Qβ—Receptor Binding Domain Conjugate
Zibin Tan,
Canchai Yang,
Po‐han Lin
et al.
Abstract:More than three years into the global pandemic, SARS‐CoV‐2 remains a significant threat to public health. Immunities acquired from infection or current vaccines fail to provide long term protection against subsequent infections, mainly due to their fast‐waning nature and the emergence of variants of concerns (VOCs) such as Omicron. To overcome these limitations, SARS‐CoV‐2 Spike protein receptor binding domain (RBD)‐based epitopes were investigated as conjugates with a powerful carrier, the mutant bacteriophag… Show more
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