Induced radioactivity in a patient-specific collimator used in proton therapy

Cesana, A.; Mauro, Egidio; Silari, M.

doi:10.1016/j.nimb.2010.03.004

Cited by 12 publications

(14 citation statements)

References 16 publications

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“…Our results on dose equivalent from activation of brass aperture are similar to those reported by Cesana et al 48 where an ambient dose equivalent rate of about 11-12 lSv/h was obtained at the upstream surface of a brass block and 2-3 lSv/h at its downstream surface after 1 day cooling. The H * (10) value reduced to 2-3 lSv/h upstream and 1.5-2 lSv/h downstream after 1 month cooling.…”

Section: Isotopesupporting

confidence: 91%

“…The H * (10) value reduced to 2-3 lSv/h upstream and 1.5-2 lSv/h downstream after 1 month cooling. The brass that was used in Cesana et al 48 study was SAE 660 containing about two times more lead than C3600 used in our study. The slight difference in the H*(10) between our values and those of Cesana et al 48 could be explained by the difference in alloys used in the simulations.…”

Section: Isotopementioning

confidence: 78%

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Pitfalls of tungsten multileaf collimator in proton beam therapy

2011

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MLC is an efficient way for beam shaping and overall cost reduction device in proton therapy. However, based on this study, tungsten seems to be not an optimal material for MLC in proton beam therapy. Usage of tungsten MLC in clinic may create unnecessary risks associated with the secondary neutrons and induced radioactivity for patients and staff depending on the patient load. A careful selection of material for manufacturing of an optimal MLC for proton therapy is thus desired.

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Section: Isotopesupporting

confidence: 91%

Section: Isotopementioning

confidence: 78%

Pitfalls of tungsten multileaf collimator in proton beam therapy

2011

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“…The report of task group 136 of the American Association of Physicists in Medicine proposed to survey activated materials routinely and dispose or recycle the patient-specific consumable components after completing the course of PBT and decay to the background has occurred. 11 Additionally, although handling of the activated material on the proton beam lines, such as the range compensator and the brass collimator, has been discussed, 12 , 13 the effect of the activation of metals inside the human body, such as dental metal, has not been clarified in PBT and is not specified in the guideline. In the present study, we revealed that the induced radionuclides with half-lives of several hours were produced from the dental metals commonly used in Japan.…”

Section: Discussionmentioning

confidence: 99%

“…Therefore, the radioactivation effects of induced radionuclides and their radiation exposure have been investigated. 12 , 13 These studies report the radioactivation of materials outside the human body. However, the radioactivation effect caused by materials inside the human body, such as dental metal, is yet to be clarified.…”

Section: Introductionmentioning

confidence: 99%

Identification of Induced Radionuclides Produced from Dental Metals in Proton Beam Therapy for Head and Neck Cancer

Kato

Katō

Narita

et al. 2023

Advances in Radiation Oncology

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“…The activated materials are generally subject to radiation control via the emission of radiation such as beta and gamma rays [2]. Several studies have reported the radioactivation effects of patient-specific devices in PBT [3,4]. Although they researched the radioactivation of materials outside a human body, it may also occur in patients following irradiation in PBT, and several reports have focused on this phenomenon for real-time monitoring and range verification by positron emission tomography imaging [5][6][7][8][9].…”

Section: Introductionmentioning

confidence: 99%

Radioactivation effects of titanium caused by clinical proton beam: a simulation study

Kato,

Murakami

2024

Biomed. Phys. Eng. Express

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Objective. In proton beam therapy (PBT), metals in the patient body perturb the dose distribution, and their radioactivation may affect the dose distribution around the metal; however, the radioactivation effect has been not clarified with PBT. In this study, we aimed to evaluate the radioactivation effect of metal depending on proton energies and secondary neutrons with a clinical proton beam using a Monte Carlo (MC) simulation.Approach. The radionuclides produced from a titanium alloy (Ti-6Al-4V) and their radioactivity were calculated using a 210-MeV passive scattering proton beam with a 60-mm Spread-out Bragg Peak, and the deposited doses caused by the radioactivation were computed using the MC simulation. The position of metal was changed according to the proton mean energy in water. To assess neutron effects on the radioactivation, we calculated the radioactivation in following three situations: (i) full MC simulation with neutrons, (ii) simulation without secondary neutrons generated from the beamline components, and (iii) simulation without any secondary neutrons.Main results. Immediately after the irradiation, the radionuclide with the largest activity was Sc-45 m (half-life of 318 ms) regardless of the proton energy and the presence of neutrons. Total radioactivity tended to increase according to the proton energy. The accumulated dose for 24 h caused by the metal activation showed an increasing trend with the proton energy, with a maximum increase rate of 0.045% to the prescribed dose. The accumulated dose at a distance of 10 mm from the metal was lower than 1/10 of that at a distance of 1 mm.Significance. The radioactivation effect of the titanium was comprehensively evaluated in the clinical passive scattering proton beam. We expect that radioactivation effects on the clinical dose distribution would be small. We consider that these results will help the clinical handling of high-Z metals in PBT.

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Induced radioactivity in a patient-specific collimator used in proton therapy

Cited by 12 publications

References 16 publications

Pitfalls of tungsten multileaf collimator in proton beam therapy

Pitfalls of tungsten multileaf collimator in proton beam therapy

Identification of Induced Radionuclides Produced from Dental Metals in Proton Beam Therapy for Head and Neck Cancer

Radioactivation effects of titanium caused by clinical proton beam: a simulation study

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