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citations
Cited by 89 publications
(48 citation statements)
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References 7 publications
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“…After detailed review of all eligible articles, 17 met the inclusion criteria. 7,12,15,[40][41][42][43][44][45][46][47][48][49][50][51][52][53] The weighted kappa on agreement between the reviewers in identifying eligible articles was 0.87, which is consistent with near perfect agreement. Reasons for excluding the potentially relevant articles included the wrong population, the wrong intervention, no control group, estimated blood loss not recorded as an outcome, subjects not randomized to treatment groups, and the article being a review or editorial.…”
Section: Resultsmentioning
confidence: 64%
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“…After detailed review of all eligible articles, 17 met the inclusion criteria. 7,12,15,[40][41][42][43][44][45][46][47][48][49][50][51][52][53] The weighted kappa on agreement between the reviewers in identifying eligible articles was 0.87, which is consistent with near perfect agreement. Reasons for excluding the potentially relevant articles included the wrong population, the wrong intervention, no control group, estimated blood loss not recorded as an outcome, subjects not randomized to treatment groups, and the article being a review or editorial.…”
Section: Resultsmentioning
confidence: 64%
“…In the studies which described the intraoperative blood pressure of the treatment group, the measured mean blood arterial ranged from 48 to 78 mmHg. The transfusion trigger was not reported in eight of the studies, 7,12,15,[41][42][43]51,52 it was left to the discretion of the attending anesthesiologist in two studies 49,50 and it was explicitly stated in the remaining seven studies. 40,[44][45][46][47][48]53 In the studies which described the transfusion triggers, the triggers included volume of blood loss (300-400 mL), hematocrit thresholds (28-30%), and percentage of blood volume lost (20%).…”
mentioning
confidence: 99%
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“…Prior studies of SNP have primarily examined: 1) clinical outcomes secondary to BP changes, such as amount of blood loss, recovery time, etc. ; 3,8,9 or 2) physiologic features such as cerebral oxygenation, mixed venous oxygen saturation, or rebound tachycardia. [15][16][17][18] There are no data describing how the practice of deliberate hypotension varies with respect to time spent in satisfactory BP control and the frequency and magnitude of dose titrations necessary to achieve said control.…”
Section: Discussionmentioning
confidence: 99%
“…Lower BPs lead to reduced blood loss, decrease the need for blood transfusion, and improve visibility in the surgical field. [1][2][3] Deliberate hypotension may be achieved using a variety of agents including anesthetic gases, beta-blockers, calciumchannel blockers, or vasodilatory drugs. [4][5][6] Sodium nitroprusside (SNP) is a direct-acting vasodilator commonly used for reduction of BP.…”
Section: Introductionmentioning
confidence: 99%