Induced hypotension with labetalol for orthognathic surgery

Effect of induced hypotensive anaesthesia vs isovolaemic haemodilution on blood loss and transfusion requirements in orthognathic surgery: a prospective, single-blinded, randomized, controlled clinical study

“…1-3), which confirms its effectiveness in orthognathic surgery 6,15,19,[26][27][28] . No further blood-sparing effect was achieved by the additional use of isovolaemic haemodilution.…”

Effect of induced hypotensive anaesthesia vs isovolaemic haemodilution on blood loss and transfusion requirements in orthognathic surgery: a prospective, single-blinded, randomized, controlled clinical study

“…1-3), which confirms its effectiveness in orthognathic surgery 6,15,19,[26][27][28] . No further blood-sparing effect was achieved by the additional use of isovolaemic haemodilution.…”

Orthognathic surgery in a patient with von Willebrand disease

“…The surgeon's technical ability and experience also play a role, as demonstrated by Yu et al 15 (2000), who emphasized that blood loss during bimaxillary orthognathic surgery is directly proportional to the surgical time and extent of the procedure. Similarly, Dhariwal et al 16 (2004) reported that the estimated blood loss in normoreactive patients undergoing bimaxillary osteotomies ranges from 50 to 500 mL, and this level of loss can be reduced by up to 50% when induced hypotension is used during anesthesia [17][18][19] . In the present case, induced hypotension was used during the anesthetic procedure, resulting in minimal recorded blood loss, highlighting its value.…”

A Comparison of Labetalol and Nitroprusside for Inducing Hypotension During Major Surgery

“…Hypotension was achieved with a mean dose of 52 mg in the halothane group and 60 mg in the isoflurane group, which demonstrated that labetalol was equally effective with both anesthetics. In addition, McNulty and colleagues (7) demonstrated that labetalol given in 10-mg increments every 5-10 min allowed a satisfactory reduction in MAP to 55-60 mm Hg in patients having orthognathic surgery. These studies did not compare labetalol to other agents nor did they address the full cardiovascular or pulmonary vascular changes occurring with use of labetalol in this fashion.…”

Effect of induced hypotensive anaesthesia vs isovolaemic haemodilution on blood loss and transfusion requirements in orthognathic surgery: a prospective, single-blinded, randomized, controlled clinical study

“…1-3), which confirms its effectiveness in orthognathic surgery 6,15,19,[26][27][28] . No further blood-sparing effect was achieved by the additional use of isovolaemic haemodilution.…”

Orthognathic surgery in a patient with von Willebrand disease

“…The surgeon's technical ability and experience also play a role, as demonstrated by Yu et al 15 (2000), who emphasized that blood loss during bimaxillary orthognathic surgery is directly proportional to the surgical time and extent of the procedure. Similarly, Dhariwal et al 16 (2004) reported that the estimated blood loss in normoreactive patients undergoing bimaxillary osteotomies ranges from 50 to 500 mL, and this level of loss can be reduced by up to 50% when induced hypotension is used during anesthesia [17][18][19] . In the present case, induced hypotension was used during the anesthetic procedure, resulting in minimal recorded blood loss, highlighting its value.…”

A Comparison of Labetalol and Nitroprusside for Inducing Hypotension During Major Surgery

“…Hypotension was achieved with a mean dose of 52 mg in the halothane group and 60 mg in the isoflurane group, which demonstrated that labetalol was equally effective with both anesthetics. In addition, McNulty and colleagues (7) demonstrated that labetalol given in 10-mg increments every 5-10 min allowed a satisfactory reduction in MAP to 55-60 mm Hg in patients having orthognathic surgery. These studies did not compare labetalol to other agents nor did they address the full cardiovascular or pulmonary vascular changes occurring with use of labetalol in this fashion.…”

Effect of induced hypotensive anaesthesia vs isovolaemic haemodilution on blood loss and transfusion requirements in orthognathic surgery: a prospective, single-blinded, randomized, controlled clinical study

“…1-3), which confirms its effectiveness in orthognathic surgery 6,15,19,[26][27][28] . No further blood-sparing effect was achieved by the additional use of isovolaemic haemodilution.…”

Orthognathic surgery in a patient with von Willebrand disease

“…The surgeon's technical ability and experience also play a role, as demonstrated by Yu et al 15 (2000), who emphasized that blood loss during bimaxillary orthognathic surgery is directly proportional to the surgical time and extent of the procedure. Similarly, Dhariwal et al 16 (2004) reported that the estimated blood loss in normoreactive patients undergoing bimaxillary osteotomies ranges from 50 to 500 mL, and this level of loss can be reduced by up to 50% when induced hypotension is used during anesthesia [17][18][19] . In the present case, induced hypotension was used during the anesthetic procedure, resulting in minimal recorded blood loss, highlighting its value.…”

A Comparison of Labetalol and Nitroprusside for Inducing Hypotension During Major Surgery

“…Hypotension was achieved with a mean dose of 52 mg in the halothane group and 60 mg in the isoflurane group, which demonstrated that labetalol was equally effective with both anesthetics. In addition, McNulty and colleagues (7) demonstrated that labetalol given in 10-mg increments every 5-10 min allowed a satisfactory reduction in MAP to 55-60 mm Hg in patients having orthognathic surgery. These studies did not compare labetalol to other agents nor did they address the full cardiovascular or pulmonary vascular changes occurring with use of labetalol in this fashion.…”