Indigenous Peoples, Consent and Benefit Sharing

Wynberg, Rachel; Schroeder, Doris; Chennells, Roger

doi:10.1007/978-90-481-3123-5

Cited by 49 publications

(1 citation statement)

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“…Around 2000 years ago, East-African pastoralists arrived in Southern Africa, and admixed with the local San populations [1, 2, 9, 10, 11], which gave rise to the Khoekhoe herding groups. Today, Khoe-San is the term used to refer to both populations collectively; the hunter-gatherer San and the herder Khoekhoe [12, 13]. The arrival of East-African pastoralists was followed by the arrival of Bantu-speaking groups practicing agriculture and carrying West African ancestry around 1800 years ago as part of the Bantu expansion [14, 15, 16, 17, 18].…”

Section: Introductionmentioning

confidence: 99%

Wide-scale Geographical Analysis of Genetic Ancestry in the South African Coloured Population

Lankheet,

Hammarén,

Caballero

et al. 2024

Preprint

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The South African Coloured (SAC) population, a prominent admixed population in South Africa, reflects centuries of migration, admixture, and historical segregation. Descendants of local Khoe-San and Bantu-speaking populations, European settlers, and enslaved individuals from Africa and Asia, SAC individuals embody diverse ancestries. This study investigates the genetic makeup of SAC individuals, utilizing autosomal genotypes, mitochondrial DNA and Y-chromosome data. We analyze new genotype data for 125 SAC individuals from seven locations. Our analysis, based on a dataset comprising 356 SAC individuals from 22 geographic locations, revealed significant regional variations in ancestry. Khoe-San ancestry predominates in 14 locations, highlighting its lasting influence. Inland regions exhibit higher proportions of Khoe-San ancestry, eastern regions show more Bantu-speaker/West African ancestry, and western/coastal areas, particularly around Cape Town, display increased Asian ancestry. These patterns reflect historical migrations and settlement patterns. Additionally, sex-biased admixture ratios show male-biased admixture from East Africans and Europeans, and female-biased admixture from Khoe-San populations, which is supported by mitochondrial and Y-chromosome data. This research underscores the importance of studying the SAC population to understand South Africa’s historical migrations, providing insights into the complex genetic heritage of South Africans.

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Section: Introductionmentioning

confidence: 99%

Wide-scale Geographical Analysis of Genetic Ancestry in the South African Coloured Population

Lankheet,

Hammarén,

Caballero

et al. 2024

Preprint

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International Research Ethics

Schüklenk¹,

Philpott²

2013

The International Encyclopedia of Ethics

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Research ethics came into its own as an ongoing academic and regulatory concern in the aftermath of the Nuremberg Trials. Knowledge of the Nazi experiments led to the first international guidelines stipulating basic ethics standards for research involving human participants (Trials of War Criminals before the Nuremberg Military Tribunals under Control Council Law 1994 [1949]). Subsequent scandals – including but not limited to the Tuskegee syphilis study – led to further and improved ethics guidelines such as the World Medical Association's Declaration of Helsinki (World Medical Association 1964–2008) as well as such national documents as the landmark Belmont Report in the USA (National Commission for the Protection of Human Subjects of Biomedical and Behavioral Research 1979).

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International Research Ethics

Schuklenk

2024

International Encyclopedia of Ethics

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Research ethics came into its own as an ongoing academic and regulatory concern in the aftermath of the Nuremberg trials. Knowledge of the Nazi experiments led to the first international guidelines stipulating basic ethics standards for research involving human participants. Subsequent scandals – including but not limited to the Tuskegee syphilis study – led to further and improved ethics guidelines such as the World Medical Association's Declaration of Helsinki as well as such national regulatory documents as the landmark Belmont Report in the United States. Academic and policy analyses in research ethics are marked by reasonably clear dividing lines between clinical and nonclinical investigations, as well as between research conducted in developed countries and research in developing countries. A few issues cut across these dividing lines, such as concerns about academic misconduct like the falsification of data, arguments about legitimate claims to authorship of a scientific publication, and plagiarism. Most of the latter concerns have been successfully addressed in international guidance documents.

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Indigenous Peoples, Consent and Benefit Sharing

Cited by 49 publications

References 100 publications

Wide-scale Geographical Analysis of Genetic Ancestry in the South African Coloured Population

Wide-scale Geographical Analysis of Genetic Ancestry in the South African Coloured Population

International Research Ethics

International Research Ethics

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