J. Clin. Lab. Anal. volume 28, issue 2, P83-90 2013 DOI: 10.1002/jcla.21648 View full text
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Belén Redal-Baigorri, Knud Rasmussen, James Goya Heaf

Abstract: BSA-GFR in patients with a BSA <1.60 m(2) overestimated GFR with a bias of 10.08 ml/min (11.46%) and underestimated GFR in those with a BSA >2 m(2) with a bias up to -20.76 ml/min (-23.59%). BSA is not a good normalization index (NI) in patients with extreme body sizes. Therefore, until a better NI is found, we recommend clinicians to use the absolute GFR to calculate individual drug chemotherapy dosage as well as express individual kidney function.