Dariusz Szukiewicz, Danuta Maslinska, Paweł Poppe, Donat Jagus
AbstractThe hypersensitivity in response to many vasoactive agents in preeclampsia (PE) may be mediated by prostanoids. Serotonin (5-HT)-induced vasoconstriction is in part mediated by thromboxane A 2 (TXA 2 ) release. The human placenta is able to produce considerable amounts of both thromboxane and prostaglandins. Thus, the eicosanoids may play an important role in the local regulation of blood flow through the fetoplacental unit under normal and pathological conditions. The goal of the study was to evaluat…
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