Increased Risk of Migraine in Patients with Temporomandibular Disorder: A Longitudinal Follow-Up Study Using a National Health Screening Cohort

Abstract

Background: The aim of this study was to investigate the association between temporomandibular disorder (TMD) and migraine through a longitudinal follow-up study using population data from a national health screening cohort. Methods: This cohort study used data from the Korean National Health Insurance Service-Health Screening Cohort from 2002 to 2015. Of the 514,866 participants, 3884 TMD patients were matched at a 1:4 ratio with 15,536 control participants. Crude models and models adjusted for obesity, smoking, alcohol consumption, systolic blood pressure, diastolic blood pressure, fasting blood glucose, total cholesterol, and Charlson Comorbidity Index (CCI) scores were calculated. Chi-squared test, Kaplan–Meier analysis, and two-tailed log-rank test were used for statistical analysis. Stratified Cox proportional hazard models were used to assess hazard ratios (HR) and 95% confidence intervals (CIs) for migraine in both control groups. Results: The adjusted HR for migraine was 2.10 (95% CI: 1.81–2.44) in the TMD group compared to the control group, which was consistent in subgroup analyses according to age, sex, and Kaplan–Meier analysis. Conclusions: This study demonstrated that TMD patients have a higher risk of migraine. These results suggest that dentists can decrease the risk of migraine in TMD patients by managing TMD properly.

Physiotherapy Management of Migraine Pain: Facial Proprioceptive Neuromuscular Facilitation Technique Versus Connective Tissue Massage

“…31,32 In some of these studies, it was stated that individuals with temporomandibular joint disorder (TMD) and occlusion problems have a higher risk of migraine. 33,34 In addition, depression and anxiety are also known to be associated with TMD disorders. 35 Depression and anxiety symptoms have also been reported as common symptoms in migraine patients.…”

Increased Risk of Temporomandibular Joint Disorder in Osteoporosis Patients: A Longitudinal Study

“…TMD was defined as a diagnosis of K07.6 (temporomandibular joint disorders). Participants who visited the clinic ≥ 2 times and were diagnosed with code K07.6 were included ( 19 ). The date of outcome event (diagnosis of TMD) was defined as the date of initial diagnosis of TMD.…”

Association between Temporomandibular Joint Disorder and Weight Changes: A Longitudinal Follow-Up Study Using a National Health Screening Cohort

“…The participants had been diagnosed under the diagnostic code for TMJD (ICD-10: K07.6 (temporomandibular joint disorders)). Participants who had histories of two or more clinical visits presenting with TMJD were included [9,12].…”

“…It results in problems in the oral preparatory phase with solid (33%) and liquid (28%) swallowing [8]. TMD can cause headaches, neck pain, body pain, and dietary problems [9,10]. It has also been reported that TMD can cause weight loss (26%) [8].…”