Increased carotid artery intima-media thickness and impaired endothelial function in psoriasis

Balci, DD; Balcı, Ali; Karazincir, Sinem; Arroyo-Úcar, Eduardo; Iyigun, U; Yalçın, Fatih; Seyfelì, Ergün; İnandı, Tacettin; Eğilmez, Ertuğrul

doi:10.1111/j.1468-3083.2008.02936.x

Cited by 174 publications

(195 citation statements)

References 33 publications

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“…Recent studies revealed psoriasis as an independent risk factor for atherosclerosis, myocardial infarction, endothelial dysfunction, coronary artery disease, stroke and diabetes [3,10,22,23,24]. A recent study emphasized the comparable increase in major adverse CV events and CV deaths in patients with severe psoriasis and diabetes [25].…”

Section: Discussionmentioning

confidence: 99%

Epicardial Fat Thickness Is Independently Associated with Psoriasis

Akyıldız¹,

Seremet

Emren³

et al. 2013

Dermatology

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Background: Several studies have showed an association between psoriasis and cardiovascular (CV) diseases and metabolic syndrome (MS). Assessment of CV risk in patients with psoriasis has become an important issue. Epicardial fat thickness (EFT) is an emerging cardiometabolic risk factor and has been shown to be related to atherosclerosis. EFT has not been studied in the context of psoriasis. Objective: To compare the EFT in psoriasis patients with that in control subjects. Methods: 31 patients with psoriasis and 32 control subjects were included in this case-control study. EFT was evaluated by two-dimensional transthoracic echocardiography. Results: EFT was significantly higher in psoriasis patients compared to controls (p = 0.027). Multiple linear regression analysis showed that the association of EFT with psoriasis was independent of MS and age. Conclusion: EFT, which has been suggested as a cardiometabolic risk factor in various diseases, is also independently associated with psoriasis.

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Section: Discussionmentioning

confidence: 99%

Epicardial Fat Thickness Is Independently Associated with Psoriasis

Akyıldız¹,

Seremet

Emren³

et al. 2013

Dermatology

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“…Endothelial dysfunction has been recognized as an early marker of subclinical atherosclerosis. FMD measurements are commonly used to evaluate endothelial function, and Balci et al [34] showed that psoriatic patients had lower FMD values than normal controls. Gonzalez-Juanatey et al [35] also demonstrated that the FMD percentage was lower in psoriatic patients.…”

Section: Discussionmentioning

confidence: 99%

Chemerin as a marker of subclinical cardiac involvement in psoriatic patients

et al. 2017

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“…Nos doentes psoriáticos, a EIM carotídea era maior nos indivíduos mais idosos, com doença mais prolongada e mais grave. Num estudo realizado por Baci et al 21 também se observou um aumento significativo da EIM das artérias carótida comum esquerda e direita nos doentes psoriáticos. O aumento na EIM carotídea dos doentes psoriáti-cos foi igualmente demonstrado por Arias-Santiago et al 22 A rigidez arterial é um preditor de eventos cardiovasculares adversos.…”

Section: Ateroscleroseunclassified

Psoríase e Doença Cardiovascular: Impacto da Terapêutica com Inibidores do TNF-alfa

Andrade

Ferreira

Torres

2018

SPDV

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RESUMO -A psoríase é uma doença inflamatória crónica que atinge 2 a 3% da população. Vários estudos têm demonstrado que a psoríase se associa a um aumento de risco de doença cardiovascular devido ao aumento da prevalência de fatores de risco cardiovasculares tradicionais, e à inflamação sistémica crónica que promove o desenvolvimento de disfunção endotelial e aterosclerose prematura. Esta revisão da literatura tem como objetivo avaliar o impacto dos inibidores do fator de necrose tumoral alfa na função endotelial e no risco de doença cardiovascular nos doentes com psoríase moderada a grave. Os estudos realizados até ao momento sugerem que o tratamento da psoríase com estes fármacos se associa a melhoria dos marcadores de disfunção endotelial e aterosclerose subclínica e a diminuição do risco de doença cardiovascular. PALAVRAS-CHAVE -

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Increased carotid artery intima-media thickness and impaired endothelial function in psoriasis

Abstract: Background Psoriasis is associated with an increased risk of atherosclerosis. This study compared subclinical

Cited by 174 publications

References 33 publications

Epicardial Fat Thickness Is Independently Associated with Psoriasis

Epicardial Fat Thickness Is Independently Associated with Psoriasis

Chemerin as a marker of subclinical cardiac involvement in psoriatic patients

Psoríase e Doença Cardiovascular: Impacto da Terapêutica com Inibidores do TNF-alfa

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