Incontinentia Pigmenti in Japan

Incontinentia Pigmenti

“…Probably most patients with incontinentia pigm enti have only the cutaneous m anifestations. Mental retardation, epilepsy and spastic tetraplegia m ay be noted [4,6,8,11,14,15], as in our three institution alized patients.…”

“…This patient had a patchy alopecia of the scalp also noted in our family study. This is a fairly frequent finding in in continentia pigm enti [4,6,14]. Strabism us has also been reported, although less frequently [4].…”

“…Defects of any portion of the eyeball may be noted in about 25 per cent of the patients with incontinentia pigmenti according to Findlay [9]. A clini cal picture similar to retrolental fibroplasia is probably the most frequent ocular complication [2,9,14].…”

Ultrastructural Studies on Pigmented Macules of Peutz‐jeghers Syndrome

“…We sometimes see a patient whith a few pigmented macules (P.M.) on the lips, fingers and toes, but have difficulty in making a diagnosis when gastrointestinal polyps are not detected. Localization of the pigmentation in the crista profunda intermedia has been described as a distinctive feature of P.M. on the fingers (3)(4)(5). However, this is not an invariable finding and it therefore seems that more definitive symptoms need to be By Invitation: Received and accepted for publication March 13, 1981. Department of Dermatology, University of Tokyo.…”

A Case of Incontinentia Pigmenti

“…Naegeli [23] already regarded the skin condition as a familial chromatophore nevus, while Hecker -following on O'Donnell's [26] summarizing paper -spoke of a nevoid inflammatory disturbance which appears at or shortly after birth. Kitamura et al [20] mentioned consanguinity, heredity and familial incidence. Epstein, Vedder and Pinkus [9] suggested that the "clinical pigmentation is secondary and a reaction to an epidermal abnormality which must have originated during fetal life, if it is not genetically fixed" .…”