Incontinence after Intersphincteric Resection

Abstract

Complications after intersphincteric resection related to defecation disorder include increase in stool frequency, urgency of defecation, and fecal incontinence. When the use of an absorbent pad is continued, the defecation function improves over time and then levels out after approximately two years. Anal manometry is used to monitor the defecation function, but there is often a poor correlation between the findings from manometry and the actual defecation situation. Proctectomy preserving the anus has decreased retention and stool storage function, and retention of the intestinal tract contents is difficult. The sphincter muscle of the anus is weakened by ISR, incurring functional disturbance and defecation abnormality with decreased QOL for the patient. Changes in physiological function are caused not only by operative anatomical changes but also by the therapeutic methods including preoperative chemoradiotherapy, reconstruction method, and any complications such as anastomotic leakage. In order to improve the indications for surgery and reduce postoperative functional disorders, further studies and more precise preoperative evaluation methods are needed.

Vitreous Humor Positive for DNA of Human Herpesvirus 7 in Eye With Ocular Toxoplasmosis

“…On the other hand, Inoue et al reported on patients with corneal endotheliitis in which genomic DNA for HHV-7 was detected by PCR analysis in the aqueous humor samples [ 3 ]. In addition, Shimomura used multiplex real-time PCR and detected the DNA of HHV-7 in the tear fluid before and after phacoemulsification and aspiration cataract surgery and after penetrating keratoplasty [ 2 ]. There have not been any reports of HHV-7 being detected in the vitreous fluid except for our case.…”

“…Human herpesvirus 7 (HHV-7) infections have been associated with roseola infantum, acute hemiplegia of childhood, respiratory tract infections, and hepatitis. It has been reported that the DNA of T. gondii can be detected in the vitreous humor [ 1 ], and the DNA of HHV-7 can be detected in the tear fluid of patients before and after cataract surgery or after penetrating keratoplasty [ 2 ] and in the aqueous humor of patient with corneal endotheliitis [ 3 ]. However, to the best of our knowledge, the DNA of HHV-7 has not been detected in the vitreous.…”