Incidence of Endophthalmitis After Intra-Operative Moxifloxacin Injection in the Capsular Bag, Behind the Intra Ocular Lens, in Phacoemulsification. A Retrospective Study

Abstract

Purpose: to evaluate the efficacy and safety of intracapsular moxifloxacin injection at the end of phacoemulsification as a prophylactic measure against early and late endophthalmitis. Setting: private eye center, eye Care, Cairo, Egypt. Methods: This is a retrospective clinical registry-based study. Data was collected from patients who had phacoemulsification within the capsular bag injection of moxifloxacin at the end of surgery. 0.2 ml of moxifloxacin 0.5% ophthalmic solution was injected into the bag by placing the tip of the cannula under the capsulorhexis edge and directing the drug behind the IOL. Results: Data were collected from EMR for 10919 eyes, that underwent phacoemulsification and in the bag moxifloxacin injection between January 2015 and August 2022, 4 cases of early endophthalmitis were reported with an incidence of 0.03%, no cases of late-endophthalmitis, and no cases of toxicity. Conclusion: Intracapsular moxifloxacin injection at the end of phacoemulsification is a safe effective prophylactic measure against endophthalmitis.