Clin Pediatr (Phila) volume 59, issue 12, P1086-1091 2020 DOI: 10.1177/0009922820941247 View full text
Kathryn K. Ostermaier, Amy L. Weaver, Scott M. Myers, Ruth E. Stoeckel, Slavica K. Katusic, Robert G. Voigt

Abstract: American Academy of Pediatrics (AAP) guidelines for children with Down syndrome (DS) include assessment for celiac disease (CD), although data to support this recommendation have been inconsistent. We determined the incidence of CD among children with DS in a population-based birth cohort of children born from 1976 to 2000 in Olmsted County, Minnesota. Individuals with karyotype-confirmed DS and CD (using diagnosis codes, positive serology, and duodenal biopsies) were identified. The incidence of CD in DS was…

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