Incidence and risk factors of peritoneal dialysis-related peritonitis in elderly patients: A retrospective clinical study

Wu, Haishan; Ye, Hongjian; Huang, Rong; Chen, Yi; Wu, Juan; Yu, Xueqing; Yang, Xiao

doi:10.1177/0896860819879868

Cited by 37 publications

(44 citation statements)

References 28 publications

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“…Age is also a risk factor of vascular calci cation [17]. Some studies have shown that elderly PD patients are inclined to develop peritonitis [18], but there was no difference in the incidence of peritonitis between elderly and younger group in this study, which was consistent with a Canada study.It was reported that elderly PD patients who were 70 years old or more had no relationship with peritonitis [19], considering that elderly patients had better family,social support and were treated with advanced antibiotics.…”

Section: Discussionsupporting

confidence: 90%

Characteristics and prognostic outcome factors in elderly peritoneal dialysis patients:a prospective observational study

Sun³

2020

Preprint

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Background: This study aimed to analyze the characteristics, outcomes and prognosis factors of survival in elderly peritoneal dialysis patients, so as to better understand the status of elderly peritoneal dialysis patients and improve their quality of life.Methods: This study was a prospective, observational study that included peritoneal dialysis (PD)patients.Categorizing by age, elderly group aged ≥ 65, younger group aged < 65. Clinical characteristics, survival and transferring to hemodialysis were compared between two groups.Meanwhile, risk factors for death in elderly PD patients were explored.Results: A total of 202 PD patients were enrolled, including 61 in elderly group and 141 in younger group. Among elderly individuals,serum albumin and normalized protein catabolic rate(nPCR) decreased, the incidence of previous cardiovascular, cerebrovascular diseases and Charlson Comorbidity Index(CCI) were higher.The major primary disease in elderly patients was diabetic nephropathy, significant differences were found between elderly and younger group(P < 0.01). The mortality in elderly group was substantially higher, 27 patients (44.3%) died in elderly group and 21 patients(14.3%) died in younger group .The 1-year,2-year,3-year,4-year survival rate were 81.97%, 70.49%, 60.66%, 55.74% respectively. Cardiovascular disease was the main cause of death in elderly PD patients. Higher BMI, CCI, and previous ischemic heart disease were risk factors for long-term survival of elderly PD patients. Compared with the younger group, elderly patients were less likely to transfer to hemodialysis: 2 cases (3.3%) in elderly group and 23 cases (16.3%) in younger group. Peritonitis was the primary reason for converting to hemodialysis(HD) in both two groups.Conclusions: Poor nutrition, more complications and diabetic nephropathy were characteristics of elderly PD patients. High BMI, CCI and previous ischemic heart disease were independent predictors of death in elderly PD patients. Cardiovascular disease was the main cause of death in elderly PD patients，while the chief reason of transferring to hemodialysis was peritonitis.

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Section: Discussionsupporting

confidence: 90%

Characteristics and prognostic outcome factors in elderly peritoneal dialysis patients:a prospective observational study

Sun³

2020

Preprint

View full text Add to dashboard Cite

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“…Age is also a risk factor of vascular calci cation [15]. Some studies have shown that elderly PD patients are inclined to develop peritonitis [16], but there was no difference in the incidence of peritonitis between elderly and younger group in this study, which was consistent with a Canada study.It was reported that elderly PD patients who were 70 years old or more had no relationship with peritonitis [17], considering that elderly patients had better family social support and was treated with advanced antibiotics.…”

Section: Discussionsupporting

confidence: 90%

Characteristics and prognostic outcome factors in elderly peritoneal dialysis patients:a prospective observational study

Sun³

2020

Preprint

View full text Add to dashboard Cite

Background This study aimed to analyze the characteristics, outcomes and prognosis factors of survival in elderly peritoneal dialysis patients, so as to better understand the status of elderly peritoneal dialysis patients and improve their quality of life.Methods This study was a prospective, observational study that included peritoneal dialysis (PD)patients.Categorizing by age, elderly group is aged ≥ 65, younger group is aged < 65. Clinical characteristics, survival and transferring to hemodialysis were compared between two groups.Meanwhile, risk factors of death in elderly PD patients were explored.Results A total of 202 PD patients were enrolled, including 61 in elderly group and 141 in younger group. The comparison of baseline data between two groups: in elderly group serum albumin and normalized protein catabolic rate(nPCR) decreased, the incidence of previous cardiovascular and cerebrovascular diseases and Charlson Comorbidity Index(CCI) were higher, the major primary disease in elderly patients was diabetic nephropathy, significant differences were found between elderly and younger group(P < 0.01). The mortality in elderly group was substantially higher, 27 patients (44.3%) died in elderly group and 21 patients(14.3%) died in younger group .The 1-year,2-year,3-year,4-year survival rate were 81.97%, 70.49%, 60.66%, 55.74%,respectively. Cardiovascular disease was the main cause of death in elderly PD patients. Higher BMI 、CCI, and previous ischemic heart disease(IHD)were risk factors for long-term survival of elderly PD patients. Compared with the younger group, elderly patients were less likely to transfer to hemodialysis: 2 cases (3.3%) in elderly group and 23 cases (16.3%) in younger group. Peritonitis was primary reason for converting to hemodialysis(HD) in both two group.Conclusions Poor nutrition, more complications and diabetic nephropathy were characteristics of elderly PD patients. High BMI, CCI and previous IHD were independent predictors of death in elderly PD patients. Cardiovascular disease was the main cause of death in elderly PD patients,while the chief reason of transferring to hemodialysis was peritonitis.

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“…12,14 Due to these conditions, up to 80% of elderly patients need some degree of assistance while performing PD. [15][16][17][18] The definition of assisted PD varies in literature. 19 In the most liberal way, it is defined as 'a PD modality performed at the patient's home with the help of a healthcare technician, a community nurse, a family member, or a partner'.…”

Section: Introductionmentioning

confidence: 99%

Assisted peritoneal dialysis across Europe: Practice variation and factors associated with availability

et al. 2021

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Background: In Europe, the number of elderly end-stage kidney disease patients is increasing. Few of those patients receive peritoneal dialysis (PD), as many cannot perform PD autonomously. Assisted PD programmes are available in most European countries, but the percentage of patients receiving assisted PD varies considerably. Hence, we assessed which factors are associated with the availability of an assisted PD programme at a centre level and whether the availability of this programme is associated with proportion of home dialysis patients. Methods: An online survey was sent to healthcare professionals of European nephrology units. After selecting one respondent per centre, the associations were explored by χ 2 tests and (ordinal) logistic regression. Results: In total, 609 respondents completed the survey. Subsequently, 288 respondents from individual centres were identified; 58% worked in a centre with an assisted PD programme. Factors associated with availability of an assisted PD programme were Western European and Scandinavian countries (OR: 5.73; 95% CI: 3.07–10.68), non-academic centres (OR: 2.01; 95% CI: 1.09–3.72) and centres with a dedicated team for education (OR: 2.87; 95% CI: 1.35–6.11). Most Eastern & Central European respondents reported that the proportion of incident and prevalent home dialysis patients was <10% (72% and 63%), while 27% of Scandinavian respondents reported a proportion of >30% for both incident and prevalent home dialysis patients. Availability of an assisted PD programme was associated with a higher incidence (cumulative OR: 1.91; 95% CI: 1.21–3.01) and prevalence (cumulative OR: 2.81; 95% CI: 1.76–4.47) of patients on home dialysis. Conclusions: Assisted PD was more commonly offered among non-academic centres with a dedicated team for education across Europe, especially among Western European and Scandinavian countries where higher incidence and prevalence of home dialysis patients was reported.[Formula: see text]

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Incidence and risk factors of peritoneal dialysis-related peritonitis in elderly patients: A retrospective clinical study

Cited by 37 publications

References 28 publications

Characteristics and prognostic outcome factors in elderly peritoneal dialysis patients:a prospective observational study

Characteristics and prognostic outcome factors in elderly peritoneal dialysis patients:a prospective observational study

Characteristics and prognostic outcome factors in elderly peritoneal dialysis patients:a prospective observational study

Assisted peritoneal dialysis across Europe: Practice variation and factors associated with availability

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