Incidence and predictors of radial artery injury following transradial procedures: Yet another benefit of renin–angiotensin system blockade?

Abstract

NMD (r = 0.419, p < 0.001). RAS blockade was independently associated with protection against FMD deterioration (OR 0.241, p = 0.032), whereas RA diameter (OR 0.079, p = 0.024) and procedure time (OR 1.156, p = 0.068) (Cardiol J 2016; 23, 1: 64-70)

Long-term endothelial dysfunction after trans-radial catheterization: A meta-analytic approach

“…Immunohistochemistry studies of RAs report a loss of endothelial integrity post‐catheterization and optical coherence tomography (OCT) imaging of cannulated RAs demonstrates morphological deformations and intimal tears . We and other studies have reported a significant impairment of RA vasomotor function early (<24 h) post‐cannulation that involves both endothelium‐dependent and independent vasodilation.…”

“…The study by Yan et al reporting significant impairment in FMD/NMD of the catheterized right radial artery was excluded due to the inability to extract reliable summary statistics (mean ± SD). Three more studies, by Heiss et al, Gaudino et al, and Turan et al assessed RA function pre and post‐RA catheterization but were ineligible for inclusion in the meta‐analysis due to the early time of RA function reassessment. These studies demonstrated a significant impairment in RA function in the first hours or days post‐catheterization which is a consistent finding amongst the published literature, and not the interest of this review.…”

“…Evidence suggests that the use of radial access for coronary catheterization may adversely affect RA function due to mechanical injury and inflammation‐related processes at the access site . Immunohistochemistry studies of RAs report a loss of endothelial integrity post‐catheterization and optical coherence tomography (OCT) imaging of cannulated RAs demonstrates morphological deformations and intimal tears .…”

“…2 Evidence suggests that the use of radial access for coronary catheterization may adversely affect RA function due to mechanical injury and inflammation-related processes at the access site. [3][4][5][6][7] Immunohistochemistry studies of RAs report a loss of endothelial integrity post-catheterization 8 and optical coherence tomography (OCT) imaging of cannulated RAs demonstrates morphological deformations and intimal tears. 8 We 9 and other studies [3][4][5][6][7] have reported a significant impairment of RA vasomotor function early (<24 h) post-cannulation that involves both endothelium-dependent and independent vasodilation.…”

Randomized Trial of Compression Duration After Transradial Cardiac Catheterization and Intervention

“…The primary outcome, RAO immediately following clamp removal, occurred in 4.9% of patients in the 20-minute group and in 2.8% of the 60-minute group (P=0. 19).…”