Incarcerated Inguinal Hernia Mesh Repair: Effect on Testicular Blood Flow and Sperm Autoimmunity

Krnić, Dragan; Družijanić, Nikica; Štula, Ivana; Čapkun, Vesna; Krnić, Duška

doi:10.12659/msm.898727

Cited by 5 publications

(2 citation statements)

References 31 publications

(36 reference statements)

Supporting

Mentioning

Contrasting

Order By: Relevance

“…In addition, in 2016, Krnić et al, 28 prospectively examined 50 men. Twenty‐five of these patients underwent elective open mesh hernia repair (Group I), while group II consisted of 25 patients who had surgery for incarcerated inguinal hernia.…”

Section: Discussionmentioning

confidence: 99%

“…shown that mesh hernia repair without complication cause only a transitory change in testicular blood flow and no clinical significant autoimmune reaction. 27 In addition, in 2016, Krnić et al, 28 prospectively examined 50 men. In the present study, the sample of patients examined is the largest at the best of our knowledge until now reported.…”

Section: Discussionmentioning

confidence: 99%

See 1 more Smart Citation

Influence of inguinal hernia repair on sperm autoimmunity: The largest single center experience

et al. 2021

View full text Add to dashboard Cite

Background: Studies on immunological infertility after inguinal hernia correction are few and not very representative. Anti-sperm antibodies have been shown to reduce male fertility. Although the extent of infertility due to anti-sperm antibodies alone is not very clear, data indicates that about 8%-10% of infertile patients have immunolog- ical infertilityDesign: This retrospective study includes all infertile male patients (n = 2258) who underwent mixed antiglobulin reaction tests and urologic examination from 2000 to 2020. Sperm quality (assessed by the number of spermatozoa, their motility, vitality, and normal form) was also evaluated. Among these patients, 191 had previously undergone unilateral or bilateral inguinal hernia surgery repair. The aim of the study is to evaluate if there is a higher incidence of positive mixed antiglobulin reaction test among patients undergoing inguinal hernioplasty compared to the unselected infertile population.Results: Anti-sperm antibodies would seem to increase in both patients who performed general andrological surgery and groin hernia correction, respectively 3.48 (95% Confidence Interval: 1.70-7.10; p < 0.001) and 2.45 (95% Confidence Interval:1.01-5.99; p < 0.05) times more than the unselected infertile population.Conclusions: Mixed antiglobulin reaction test could be useful in patients undergone previous scrotal surgery or hernia correction men, to avoid false unexplained infertility diagnoses and to direct the couple to assisted reproductive technology procedures.Basal evaluation of spermatozoa does not actually consider andrological surgery as an indication to autoimmunity investigation.

show abstract

Section: Discussionmentioning

confidence: 99%

Section: Discussionmentioning

confidence: 99%

Influence of inguinal hernia repair on sperm autoimmunity: The largest single center experience

et al. 2021

View full text Add to dashboard Cite

show abstract

Immune infertility in men

Leathersich

Hart

2022

Fertility and Sterility

View full text Add to dashboard Cite

Does the use of hernia mesh in surgical inguinal hernia repairs cause male infertility? A systematic review and descriptive analysis

et al. 2018

View full text Add to dashboard Cite

ObjectiveThe aim of this study was to systematically review the available clinical trials examining male infertility after inguinal hernias were repaired using mesh procedures.MethodsThe Cochrane Library, PubMed, Embase, Web of Science, and Chinese Biomedical Medicine Database were investigated. The Jada score was used to evaluate the quality of the studies, “Oxford Centre for Evidence-based Medicine-Levels of Evidence” was used to assess the level of the trials, and descriptive analysis was used to evaluate the studies.ResultsTwenty nine related trials with a total of 36,552 patients were investigated, including seven randomized controlled trials (RCTs) with 616 patients and 10 clinical trials (1230 patients) with mesh or non-mesh repairs. The Jada score showed that there were six high quality RCTs and one low quality RCT. Levels of evidence determined from the Oxford Centre for Evidence-based Medicine further demonstrated that those six high quality RCTs also had high levels of evidence. It was found that serum testosterone, LH, and FSH levels declined in the laparoscopic group compared to the open group; however, the testicular volume only slightly increased without statistical significance. Testicular and sexual functions remained unchanged after both laparoscopic transabdominal preperitoneal hernia repair (TAPP) and totally extra-peritoneal repair (TEP). We also compared the different meshes used post-surgeries. VyproII/Timesh lightweight mesh had a diminished effect on sperm motility compared to Marlex heavyweight mesh after a one-year follow-up, but there was no effect after 3 years. Additionally, various open hernia repair procedures (Lichtenstein, mesh plug method, posterior pre-peritoneal mesh repair, and anterior tension-free repair) did not cause infertility.ConclusionsThis systematic review suggests that hernia repair with mesh either in an open or a laparoscopic procedure has no significant effect on male fertility.

show abstract

Incarcerated Inguinal Hernia Mesh Repair: Effect on Testicular Blood Flow and Sperm Autoimmunity

Cited by 5 publications

References 31 publications

Influence of inguinal hernia repair on sperm autoimmunity: The largest single center experience

Influence of inguinal hernia repair on sperm autoimmunity: The largest single center experience

Immune infertility in men

Does the use of hernia mesh in surgical inguinal hernia repairs cause male infertility? A systematic review and descriptive analysis

Contact Info

Product

Resources

About