Abstract:Considerable progress has been made in possible pathways of phospholipide synthesis in liver for partial purified enzyme systems. Recent work has provided evidence that CoA( 1 ) , ATP( 2,3), and maintenance of oxidative phosphorylation (4) are essential for phospholipide synthesis in liver mitochondria. Recently Kennedy has shown that liver mitochondria synthesize lecithins, involving phosphorylcholine as an intermediate and incorporate choline directly into the lipide molecule, requiring ATP and CTP(4,S). Pho… Show more
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