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Cited by 37 publications
(55 citation statements)
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“…For orthopaedic applications small animal studies are generally conducted in rodents such as rats or rabbits [18,27,120,121]. For larger animal studies sheep [122] and pigs [123] have been used previously, with dogs and goats also established in the field [119]. In cardiovascular applications rats are also used as a small animal model [124][125][126], with pigs generally favoured once large animal trials are required [127].…”
Section: Consideration For Selecting An Appropriate In Vivo Modelmentioning
confidence: 99%
“…For orthopaedic applications small animal studies are generally conducted in rodents such as rats or rabbits [18,27,120,121]. For larger animal studies sheep [122] and pigs [123] have been used previously, with dogs and goats also established in the field [119]. In cardiovascular applications rats are also used as a small animal model [124][125][126], with pigs generally favoured once large animal trials are required [127].…”
Section: Consideration For Selecting An Appropriate In Vivo Modelmentioning
confidence: 99%
“…Schaller et al studied plasma electrolytic coated implants in a craniofacial pig model. 51 Although they did not provide quantitative data, the coating decreased the gas pocket formation during 12 weeks after the implantation, based on the microCT and histological observations. In our experiments the AS coating reduced the gas pocket formation over the 6 weeks experiment in comparison to the uncoated samples, especially during the first 3 weeks postimplantation.…”
Section: Discussionmentioning
confidence: 99%
“…At present, passivated and highly corrosion-resistant metallic materials-e.g., the Ti-6Al-4V alloy, pure Titanium (Ti), Co-Cr alloy and 316L stainless steel, are used for MSIs and BFPs [12,13]. Surgery to remove these materials imposes a physical and economic burden upon the patient; therefore, such surgery can be avoided if bioabsorbable MSIs and BFPs were used [13,14].…”
Section: Introductionmentioning
confidence: 99%
“…Mg has been the subject of much basic and translational research. Mg readily dissolves in vivo as follows, because it has a low standard electrode potential [1], and is of low toxicity [14]:…”
Section: Introductionmentioning
confidence: 99%