In vivo Breast Sound-Speed Imaging with Ultrasound Tomography

Li, Cuiping; Duric, Nebojsa; Littrup, Peter J.; Huang, Lianjie

doi:10.1016/j.ultrasmedbio.2009.05.011

Cited by 273 publications

(204 citation statements)

References 44 publications

(50 reference statements)

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“…7,20,23,24 However, none of these methods have been efficient enough to be deployed in practice, and thus the more recent literature is dominated by straight ray propagation methods. But as was shown by Denis et al 25 and more recently by Li et al,26 nonlinear ray tracing can achieve substantial qualitative improvements over straight ray casting, even for moderately refracting fields. Yet that work did not offer efficient methods to accomplish this.…”

Section: Iib Projection Simulatormentioning

confidence: 91%

Refraction corrected transmission ultrasound computed tomography for application in breast imaging

Jackowski

Dione³

et al. 2010

Medical Physics

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Purpose:We present an iterative framework for CT reconstruction from transmission ultrasound data which accurately and efficiently models the strong refraction effects that occur in our target application: Imaging the female breast. Methods: Our refractive ray tracing framework has its foundation in the fast marching method ͑FNMM͒ and it allows an accurate as well as efficient modeling of curved rays. We also describe a novel regularization scheme that yields further significant reconstruction quality improvements. A final contribution is the development of a realistic anthropomorphic digital breast phantom based on the NIH Visible Female data set. Results: Our system is able to resolve very fine details even in the presence of significant noise, and it reconstructs both sound speed and attenuation data. Excellent correspondence with a traditional, but significantly more computationally expensive wave equation solver is achieved. Conclusions: Apart from the accurate modeling of curved rays, decisive factors have also been our regularization scheme and the high-quality interpolation filter we have used. An added benefit of our framework is that it accelerates well on GPUs where we have shown that clinical 3D reconstruction speeds on the order of minutes are possible.

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Section: Iib Projection Simulatormentioning

confidence: 91%

Refraction corrected transmission ultrasound computed tomography for application in breast imaging

Jackowski

Dione³

et al. 2010

Medical Physics

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“…This method thus preserves discontinuities on the reconstructed profiles, producing a sharp transition of conductivity over the intermedium boundaries [2].…”

Section: Introductionmentioning

confidence: 99%

Improving the performance of primal--dual interior-point method in inverse conductivity problems

Javaherian¹,

Amir²,

Faghihi³

et al. 2015

Turk J Elec Eng & Comp Sci

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This study improves the performance of primal-dual interior-point method in inverse conductivity problems via replacing the conventional, complicatedly calculated scalar regularization parameter with a diagonal matrix termed "multi-regularization parameter matrix" here. The solution of the PD-IPM depends considerably on the choice of the regularization parameter. Calculation of the optimal regularization parameter, which yields the most accurate solution, is not simple due to the long iterative nature of the algorithm. The objective optimization, which is implemented by minimizing error in the solutions over an extensive range of the regularization parameters, yields the most accurate solution that can be achieved, although this method is not applicable in reality due to lack of knowledge about the actual conductivity field. However, the modified algorithm not only solves the problem independently using the regularization parameter, but also increases the accuracy of the solution, as well as its sharpness in comparison to the objective optimization.

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“…The transmitted signal is used to reconstruct sound speed and attenuation maps of the imaged area. [12][13][14] The sound speed images are reconstructed from measurements of the signal arrival times using bent-ray techniques, while the attenuation is reconstructed from the calculated loss of wave energy along bent-ray paths. The reflection images are reconstructed using delay and sum migration techniques.…”

Section: Introductionmentioning

confidence: 99%

Modification of Kirchhoff migration with variable sound speed and attenuation for acoustic imaging of media and application to tomographic imaging of the breast

Schmidt

Duric

et al. 2011

Medical Physics

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Purpose:To explore the feasibility of improving cross-sectional reflection imaging of the breast using refractive and attenuation corrections derived from ultrasound tomography data. Methods: The authors have adapted the planar Kirchhoff migration method, commonly used in geophysics to reconstruct reflection images, for use in ultrasound tomography imaging of the breast. Furthermore, the authors extended this method to allow for refractive and attenuative corrections. Using clinical data obtained with a breast imaging prototype, the authors applied this method to generate cross-sectional reflection images of the breast that were corrected using known distributions of sound speed and attenuation obtained from the same data. Results: A comparison of images reconstructed with and without the corrections showed varying degrees of improvement. The sound speed correction resulted in sharpening of detail, while the attenuation correction reduced the central darkening caused by path length dependent losses. The improvements appeared to be greatest when dense tissue was involved and the least for fatty tissue. These results are consistent with the expectation that denser tissues lead to both greater refractive effects and greater attenuation. Conclusions: Although conventional ultrasound techniques use time-gain control to correct for attenuation gradients, these corrections lead to artifacts because the true attenuation distribution is not known. The use of constant sound speed leads to additional artifacts that arise from not knowing the sound speed distribution. The authors show that in the context of ultrasound tomography, it is possible to construct reflection images of the breast that correct for inhomogeneous distributions of both sound speed and attenuation.

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In vivo Breast Sound-Speed Imaging with Ultrasound Tomography

Cited by 273 publications

References 44 publications

Refraction corrected transmission ultrasound computed tomography for application in breast imaging

Refraction corrected transmission ultrasound computed tomography for application in breast imaging

Improving the performance of primal--dual interior-point method in inverse conductivity problems

Modification of Kirchhoff migration with variable sound speed and attenuation for acoustic imaging of media and application to tomographic imaging of the breast

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