volume 6, issue 63, P58034-58045 2016
DOI: 10.1039/c6ra08299h
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Abstract: Due to the polymer, octylamine-graft-poly (aspartic) (PASP-g-C 8 ), which acted as acidic triggered molecules, liposomes anchored with PASP-g-C 8 (OPLPs) could be safe and efficient pH sensitive drug carriers and target tumor cells. In the present study cytarabine (CYT) was chosen as the model drug and the in vitro biological stability and cytotoxicity of OPLPs were further investigated. Transmission electron microscopy (TEM) images indicated that the OPLPs remained active in both normal (pH 7.4 solution) and…

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