In vitro removal of deoxynivalenol and T-2 toxin by lactic acid bacteria

Zou, Zhongyi; He, Zhike; Zhang, Dongliang; Han, Ping; Meng, Xiao; Zhang, Yu; Fang, Zhou; Ouyang, Ke-Pei; Chen, Xi-Yue; Tang, Jun

doi:10.1007/s10068-012-0223-x

Cited by 56 publications

(45 citation statements)

References 26 publications

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“…To obtain heat-inactivated cells, bacteria were autoclaved for 20 min at 121 C as described by Zou et al (2012). A sample with 10 mg/mL activated charcoal suspended in an contaminated MRS medium at pH 3.9 (final pH of the MRS at 48 h) was selected as the positive control.…”

Section: Impact Of Bacterial Concentration and Mycotoxin Concentrationmentioning

confidence: 99%

“…During the past couple of decades, many Lactobacillus plantarum strains have shown great abilities in the detoxification of aflatoxin B1 (Fazeli et al, 2009;Haskard, El-Nezami, Kankaanp€ a€ a, Salminen, & Ahokas, 2001;Khanafari, Soudi, Miraboulfathi, & Karamei Osboo, 2007;Zinedine, Faid, & Benlemlih, 2005), patulin, ochratoxin A (Fuchs et al, 2008;Hawar et al, 2013) and deoxynivalenol and deoxynivalenol-3-glucoside (Berthiller et al, 2011;Zou et al, 2012); however, limited information is available on the abilities of L. plantarum to degrade ZEA.…”

Section: Introductionmentioning

confidence: 99%

See 1 more Smart Citation

Detoxification of zearalenone by three strains of lactobacillus plantarum from fermented food in vitro

Zhao

Jin²,

Lan³

et al. 2015

Food Control

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Section: Impact Of Bacterial Concentration and Mycotoxin Concentrationmentioning

confidence: 99%

Section: Introductionmentioning

confidence: 99%

Detoxification of zearalenone by three strains of lactobacillus plantarum from fermented food in vitro

Zhao

Jin²,

Lan³

et al. 2015

Food Control

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“…Five strains, including Lactococcus lactis 6020, Lactobacillus brevis 1.12, Lactobacillus casei 6103, Lactobacillus plantarum 8014, and Lactobacillus plantarum 102, were reported to bind DON from MRS agar. Among the strains, L. plantarum achieved the best result (Zou et al., 2012). García et al.…”

Section: Degradation Of Don By Microorganismsmentioning

confidence: 99%

Deoxynivalenol: Masked forms, fate during food processing, and potential biological remedies

Guo

Wang

et al. 2020

Comp Rev Food Sci Food Safe

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Deoxynivalenol (DON) has drawn global attention because of its prevalence and significant effects on human or animal health. Biological remedies for DON have been developed from preharvest to postharvest. Applying microbes, including bacteria, fungi (yeast and molds), and enzymes, results in inhibited synthesis, structural destruction, or adsorption of DON. DON can be degraded into masked forms by phase I metabolism or phase II metabolism. During food processing, DON content changes dynamically and is even transformed. Physical, chemical, thermal, or biological processes physically reduce DON content. Temperature, heating time, enzymes, food additives, microorganisms, food composition, contamination level, and other ingredients are key factors. Although DON content can be reduced during food processing, increases in other toxins, such as DON‐3‐β‐d‐glucoside and 3‐acetyl‐DON, can be potentially risky. The application of biodegradation methods in food processing bears research significance. Both microorganisms and enzymes can be potentially used. Novel techniques, such as RNA interference, omics technologies, or enzymes coupled with the genetic engineering method, can be introduced. This review systematically updates the understanding of masked forms of DON, biological degradation strategy, fate of DON during processing, and future trends for biodegradation. Challenges to the successful application of biological methods may include the stability and suitability of the detoxification agents, security of degradation products, and successful application for industrial production.

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“…SGF was consisted of 3.2 mg/mL pepsin (Sigma Chemical) in 0.03 M NaCl at pH 1.2, and SIF was consisted of 10 mg/mL pancreatin (Sigma Chemical) in 0.05 M KH2PO4 at pH 6.8. SGF and SIF were sterilized through 0.22 μm filters, and kept at 4C, renewed weekly and brought to room temperature before use, which were used to evaluate the stability of cell-toxin complexes to gastric conditions and small intestinal conditions (Kovacs-Nolan and Mine 2005; Zou et al 2012b). …”

Section: Preparation Of Solutionsmentioning

confidence: 99%

In Vitro Removal of T‐2 Toxin by Yeasts

Zou¹,

Sun²,

Huang³

et al. 2015

Journal of Food Safety

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Five yeast strains were tested for their ability to remove T-2 toxin from yeast extract peptone dextrose medium. The ability of Saccharomyces cerevisiae 1221 (SC1221) was the strongest among five strains, and 36.50 ± 1.40% of T-2 toxin was removed after incubation at 30C for 96 h. The mode of removal was physical binding rather than biotransformation. The total amount of T-2 toxin released from viable Saccharomyces cerevisiae 1221 cell-toxin complexes was 37.39 ± 0.48% of total bound T-2 toxin, respectively, after three times of washing with phosphate buffered saline, which was 8.17 ± 0.75% after incubation with simulated gastric fluid at 37C for 4 h, and which was 13.22 ± 0.61% after incubation with simulated intestinal fluid at 37C for 4 h, respectively. PRACTICAL APPLICATIONST-2 toxin is the most toxic trichothecene, which is commonly found in cereal grains, animal feed and human food produced from contaminated grains. The best solution for decontamination should be detoxification by microorganisms, giving a possibility for removal of mycotoxins under mild conditions, without using harmful chemicals and significant losses in nutritive value and palatability of decontaminated food and feed. Yeasts have immense potential as tools in tackling the problem of mycotoxins in cereal-based foods and in animal feeds. The objective of this work was to investigate the effect of food-grade yeast strains on the removal of T-2 toxin in vitro. Results of this study indicated that the strain of Saccharomyces cerevisiae 1221 (SC1221) has a strong ability to remove T-2 toxin. Therefore, this strain could be potentially applied in food and feed industry for detoxification of T-2 toxin.

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In vitro removal of deoxynivalenol and T-2 toxin by lactic acid bacteria

Cited by 56 publications

References 26 publications

Detoxification of zearalenone by three strains of lactobacillus plantarum from fermented food in vitro

Detoxification of zearalenone by three strains of lactobacillus plantarum from fermented food in vitro

Deoxynivalenol: Masked forms, fate during food processing, and potential biological remedies

In Vitro Removal of T‐2 Toxin by Yeasts

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